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Gpc5 Gene Detail
Summary
  • Symbol
    Gpc5
  • Name
    glypican 5
  • Synonyms
    A230034F01Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1194894
    NCBI Gene: 103978
  • Gene Overview
    MyGene.info: GPC5
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:115092215-116525179 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 59.43 cM, cytoband E4
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    4723 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1194894
protein coding gene Chr14:115092201-116525192 (+)
129S1/SvImJ MGP_129S1SvImJ_G0021644
protein coding gene Chr14:112549865-114040770 (+)
A/J MGP_AJ_G0021603
protein coding gene Chr14:108300147-109702958 (+)
AKR/J MGP_AKRJ_G0021579
protein coding gene Chr14:111831423-113283646 (+)
BALB/cJ MGP_BALBcJ_G0021609
protein coding gene Chr14:108815586-110232601 (+)
C3H/HeJ MGP_C3HHeJ_G0021387
protein coding gene Chr14:111656700-113127648 (+)
C57BL/6NJ MGP_C57BL6NJ_G0022049
protein coding gene Chr14:116881106-118455037 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019588
protein coding gene Chr14:104467326-105820784 (+)
CAST/EiJ MGP_CASTEiJ_G0020903
protein coding gene Chr14:109434925-110948393 (+)
CBA/J MGP_CBAJ_G0021355
protein coding gene Chr14:121418844-123058554 (+)
DBA/2J MGP_DBA2J_G0021478
protein coding gene Chr14:108216969-109624295 (+)
FVB/NJ MGP_FVBNJ_G0021456
protein coding gene Chr14:106562747-107958966 (+)
LP/J MGP_LPJ_G0021546
protein coding gene Chr14:113575441-115061091 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0021483
protein coding gene Chr14:126298608-128093208 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0022072
protein coding gene Chr14:111263605-112707211 (+)
PWK/PhJ MGP_PWKPhJ_G0020647
protein coding gene Chr14:105163805-106592765 (+)
SPRET/EiJ MGP_SPRETEiJ_G0020485
protein coding gene Chr14:107399961-108915039 (+)
WSB/EiJ MGP_WSBEiJ_G0020958
protein coding gene Chr14:112004909-113504366 (+)



Homology
more
  • Human Ortholog
    GPC5, glypican 5
  • Vertebrate Orthologs
    9
  • Human Ortholog
    GPC5, glypican 5
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 2262
    neXtProt AC: NX_P78333
    UniProt: P78333

  • Chr Location
    13q31.3; chr13:91398619-92867237 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000022112 Ensembl Gene Model | MGI Sequence Detail 1432965 C57BL/6J ±  kb
transcript ENSMUST00000176912 Ensembl | MGI Sequence Detail 2837 Not Applicable  
polypeptide ENSMUSP00000135085 Ensembl | MGI Sequence Detail 645 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 12
    cDNA 10
    Primer pair 2

    Microarray probesets 2
Other
Accession IDs
less
MGI:2442523
References
more
  • Summaries
    All 43
    Developmental Gene Expression 9
    Gene Ontology 4
    Phenotypes 12
  • Earliest
    J:45283 Saunders S, et al., Expression of the cell surface proteoglycan glypican-5 is developmentally regulated in kidney, limb, and brain. Dev Biol. 1997 Oct 1;190(1):78-93
  • Latest
    J:230611 Dierker T, et al., Altered heparan sulfate structure in Glce(-/-) mice leads to increased Hedgehog signaling in endochondral bones. Matrix Biol. 2016 Jan;49:82-92

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
12/03/2019
MGI 6.14
The Jackson Laboratory