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Psmb5 Gene Detail
Summary
  • Symbol
    Psmb5
  • Name
    proteasome (prosome, macropain) subunit, beta type 5
  • Feature Type
    protein coding gene
  • IDs
    MGI:1194513
    NCBI Gene: 19173
  • Gene Overview
    MyGene.info: PSMB5
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:54614120-54617995 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 27.86 cM, cytoband C2-D1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    88 from dbSNP Build 142
  • Strain Annotations
    17
  • PCR
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1194513
protein coding gene Chr14:54614119-54618022 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021316
protein coding gene Chr14:48576860-48580789 (-)
A/J MGP_AJ_G0021275
protein coding gene Chr14:47626363-47630114 (-)
AKR/J MGP_AKRJ_G0021251
protein coding gene Chr14:49343824-49354205 (-)
BALB/cJ MGP_BALBcJ_G0021279
protein coding gene Chr14:47601270-47605207 (-)
C3H/HeJ MGP_C3HHeJ_G0021059
protein coding gene Chr14:49042916-49047383 (-)
C57BL/6NJ no annotation
CAROLI/EiJ MGP_CAROLIEiJ_G0019262
protein coding gene Chr14:46041990-46046011 (-)
CAST/EiJ MGP_CASTEiJ_G0020578
protein coding gene Chr14:45282991-45286880 (-)
CBA/J MGP_CBAJ_G0021026
protein coding gene Chr14:52552576-52556465 (-)
DBA/2J MGP_DBA2J_G0021147
protein coding gene Chr14:47366533-47370304 (-)
FVB/NJ MGP_FVBNJ_G0021129
protein coding gene Chr14:46819910-46824155 (-)
LP/J MGP_LPJ_G0021221
protein coding gene Chr14:49582577-49586466 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021153
protein coding gene Chr14:51974124-51978013 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021744
protein coding gene Chr14:48538085-48541974 (-)
PWK/PhJ MGP_PWKPhJ_G0020324
protein coding gene Chr14:43896318-43900281 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020152
protein coding gene Chr14:44520092-44523977 (-)
WSB/EiJ MGP_WSBEiJ_G0020631
protein coding gene Chr14:48825356-48829323 (-)



Homology
more
  • Human Ortholog
    PSMB5, proteasome subunit beta 5
  • Vertebrate Orthologs
    8
  • Human Ortholog
    PSMB5, proteasome subunit beta 5
    Orthology source: HGNC, HomoloGene
  • Synonyms
    LMPX, MB1, X
  • Links
    NCBI Gene ID: 5693
    neXtProt AC: NX_P28074
    UniProt: P28074

  • Chr Location
    14q11.2; chr14:23016543-23035220 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 19173 NCBI Gene Model | MGI Sequence Detail 3876 C57BL/6J ±  kb
transcript NM_011186 RefSeq | MGI Sequence Detail 871 B10.A-H2  
polypeptide O55234 UniProt | EBI | MGI Sequence Detail 264 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 145
    Genomic 1
    cDNA 143
    Primer pair 1

    Microarray probesets 4
References
more
  • Summaries
    All 38
    Developmental Gene Expression 4
    Gene Ontology 9
    Phenotypes 6
  • Earliest
    J:44713 Kohda K, et al., Structural analysis and chromosomal localization of the mouse Psmb5 gene coding for the constitutively expressed beta-type proteasome subunit. Immunogenetics. 1997;47(1):77-87
  • Latest
    J:266104 Choi JH, et al., mTORC1 accelerates retinal development via the immunoproteasome. Nat Commun. 2018 Jun 27;9(1):2502

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory