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Psmb5
Gene Detail
Symbol

Name
ID
Psmb5
proteasome (prosome, macropain) subunit, beta type 5
MGI:1194513
Feature Type
protein coding gene
Genetic Map
Chromosome 14
27.86 cM, cytoband C2-D1
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr14:54614120-54617995 bp, - strand
From NCBI annotation of GRCm38

  3876 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:55690  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: PSMB5
Gene Tree: Psmb5

Human
homologs
PSMB5, proteasome subunit beta 5
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 5693
neXtProt AC: NX_P28074

Human Synonyms: LMPX, MB1, X

Human Chr (Location): 14q11.2; chr14:23016543-23035220 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Gene trapped(2) Targeted(2)
Incidental mutations (data from APF , CvDC )
Interactions
Psmb5 interacts with 6 markers (Mir139, Mir202, Mir377, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (3 records)
Data Summary: Results (1)    Tissues (1)    Images (1)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 1
cDNA source data(142)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase psmb5 ; ZFIN psmb5    NEW 
Molecular
reagents
All nucleic(144) Genomic(1) cDNA(142) Primer pair(1)
Microarray probesets(4)
Other database
links
Ensembl Gene Model ENSMUSG00000022193 (Evidence)
Entrez Gene 19173 (Evidence)
UniGene 8911
DFCI TC1572650, TC1590944, TC1744739
DoTS DT.55107717, DT.55112682
NIA Mouse Gene Index U035557, U372614
EC 3.4.25.1
PDB 3UNB, 3UNE
Consensus CDS Project CCDS27095.1
International Mouse Phenotyping Consortium Status Psmb5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 19173 NCBI Gene Model | MGI Sequence Detail 3876 C57BL/6J ±  kb
transcript NM_011186 RefSeq | MGI Sequence Detail 871 B10.A-H2 
polypeptide O55234 UniProt | EBI | MGI Sequence Detail 264 Not Applicable 

For the selected sequences
All sequences(29) RefSeq(2) UniProt(2)
Polymorphisms
PCR(1) : SNPs within 2kb(101 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR029055 Nucleophile aminohydrolases, N-terminal
InterPro IPR000243 Peptidase T1A, proteasome beta-subunit
InterPro IPR016050 Proteasome beta-type subunit, conserved site
InterPro IPR023333 Proteasome B-type subunit
InterPro IPR001353 Proteasome, subunit alpha/beta
Protein Ontology PR:000013373 proteasome subunit beta type-5
Graphical View of Protein Domain Structure
References
(Earliest) J:44713 Kohda K, et al., Structural analysis and chromosomal localization of the mouse Psmb5 gene coding for the constitutively expressed beta-type proteasome subunit. Immunogenetics. 1997;47(1):77-87
(Latest) J:191966 Wang X, et al., Pno1 tissue-specific expression and its functions related to the immune responses and proteasome activities. PLoS One. 2012;7(9):e46093
All references(33)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory