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Psmb5 Gene Detail
Summary
  • Symbol
    Psmb5
  • Name
    proteasome (prosome, macropain) subunit, beta type 5
  • Feature Type
    protein coding gene
  • IDs
    MGI:1194513
    NCBI Gene: 19173
  • Gene Overview
    MyGene.info: PSMB5
Location & Maps
more
  • Sequence Map
    Chr14:54614120-54617995 bp, - strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      3876 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 27.86 cM, cytoband C2-D1
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    PSMB5, proteasome subunit beta 5
  • Vertebrate Orthologs
    8
  • Human Ortholog
    PSMB5, proteasome subunit beta 5
    Orthology source: HomoloGene
  • Synonyms
    LMPX, MB1, X
  • Links
    NCBI Gene ID: 5693
    neXtProt AC: NX_P28074

  • Chr Location
    14q11.2; chr14:23016543-23035220 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    1
  • Gene trapped
    2
  • Targeted
    2
  • Genomic Mutations
    1 involving Psmb5
  • Incidental Mutations
    APF , CvDC
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 19173 NCBI Gene Model | MGI Sequence Detail 3876 C57BL/6J ±  kb
transcript NM_011186 RefSeq | MGI Sequence Detail 871 B10.A-H2  
polypeptide O55234 UniProt | EBI | MGI Sequence Detail 264 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    88 from dbSNP Build 142
  • PCR
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 144
    Genomic 1
    cDNA 142
    Primer pair 1

    Microarray probesets 4
References
more
  • Summaries
    All 30
    Developmental Gene Expression 3
    Gene Ontology 7
    Phenotypes 6
  • Earliest
    J:44713 Kohda K, et al., Structural analysis and chromosomal localization of the mouse Psmb5 gene coding for the constitutively expressed beta-type proteasome subunit. Immunogenetics. 1997;47(1):77-87
  • Latest
    J:191966 Wang X, et al., Pno1 tissue-specific expression and its functions related to the immune responses and proteasome activities. PLoS One. 2012;7(9):e46093

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
06/22/2016
MGI 6.04
The Jackson Laboratory