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Ddost
Gene Detail
 Symbol
Name
ID
Ddost
dolichyl-di-phosphooligosaccharide-protein glycotransferase
MGI:1194508
Feature Type protein coding gene
Genetic Map
Chromosome 4
70.13 cM, cytoband D3
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr4:138304730-138312628 bp, + strand
From VEGA annotation of GRCm38

  7899 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3821  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: dolichyl-diphosphooligosaccharide--protein glycosyltransferase, DDOST beta (WBP1) subunit type
Gene Tree: Ddost

Human
homologs
Human Homolog DDOST, dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)
NCBI Gene ID 1650
neXtProt AC  NX_P39656
Human Synonyms  AGER1, CDG1R, OKSWcl45, OST, OST48, WBP1
Human Chr (Location)  1p36.1; chr1:20651767-20661544 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human DDOST
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(2) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Ddost interacts with 121 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (13 annotations)
Process protein N-linked glycosylation, protein N-linked glycosylation via asparagine, ...
Component endoplasmic reticulum, endoplasmic reticulum membrane, ...
Function dolichyl-diphosphooligosaccharide-protein glycotransferase activity, transferase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (95)    Tissues (95)    Images (14)
Theiler Stages: 22
Assay TypeResults
RNA in situ 95
cDNA source data(9)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(9) cDNA(9)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000009976 (Evidence)
Ensembl Gene ModelENSMUSG00000028757 (Evidence)
Entrez Gene13200 (Evidence)
DFCITC1571959
DoTSDT.91369920
NIA Mouse Gene IndexU004997, U101177
EC2.4.99.18
Consensus CDS ProjectCCDS18824.1
International Mouse Knockout Project StatusDdost
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000009976 VEGA Gene Model | MGI Sequence Detail 7899 C57BL/6J ±  kb
transcript OTTMUST00000023187 VEGA | MGI Sequence Detail 2120 Not Applicable 
polypeptide OTTMUSP00000010583 VEGA | MGI Sequence Detail 441 Not Applicable 

For the selected sequences
All sequences(31) RefSeq(2) UniProt(3)
Polymorphisms SNPs within 2kb(237 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR005013 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit WBP1
Protein Ontology PR:000006352 dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit
References (Earliest) J:44254 Yamagata T, et al., Genome organization of human 48-kDa oligosaccharyltransferase (DDOST). Genomics. 1997 Nov 1;45(3):535-40
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(35)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory