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Ddost
Gene Detail
Symbol

Name
ID
Ddost
dolichyl-di-phosphooligosaccharide-protein glycotransferase
MGI:1194508
Feature Type
protein coding gene
Genetic Map
Chromosome 4
70.13 cM, cytoband D3
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr4:138304730-138312628 bp, + strand
From VEGA annotation of GRCm38

  7899 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3821  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: DDOST
Protein SuperFamily: dolichyl-diphosphooligosaccharide--protein glycosyltransferase, DDOST beta (WBP1) subunit type
Gene Tree: Ddost

Human
homologs
DDOST, dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 1650
neXtProt AC: NX_P39656

Human Synonyms: AGER1, CDG1R, OKSWcl45, OST, OST48, WBP1

Human Chr (Location): 1p36.1; chr1:20651767-20661544 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human DDOST

Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Gene trapped(2) Targeted(4)
Genomic Mutations involving Ddost (1)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Ddost interacts with 121 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Expression
Literature Summary: (2 records)
Data Summary: Results (95)    Tissues (95)    Images (14)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 95
cDNA source data(9)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase ddost ; ZFIN ddost    NEW 
Molecular
reagents
All nucleic(9) cDNA(9)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000009976 (Evidence)
Ensembl Gene Model ENSMUSG00000028757 (Evidence)
Entrez Gene 13200 (Evidence)
DFCI TC1571959
DoTS DT.91369920
NIA Mouse Gene Index U004997, U101177
EC 2.4.99.18
Consensus CDS Project CCDS18824.1
International Mouse Phenotyping Consortium Status Ddost
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000009976 VEGA Gene Model | MGI Sequence Detail 7899 C57BL/6J ±  kb
transcript OTTMUST00000023187 VEGA | MGI Sequence Detail 2120 Not Applicable 
polypeptide OTTMUSP00000010583 VEGA | MGI Sequence Detail 441 Not Applicable 

For the selected sequences
All sequences(34) RefSeq(2) UniProt(3)
Polymorphisms
SNPs within 2kb(237 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR005013 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit WBP1
Protein Ontology PR:000006352 dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit
References
(Earliest) J:44254 Yamagata T, et al., Genome organization of human 48-kDa oligosaccharyltransferase (DDOST). Genomics. 1997 Nov 1;45(3):535-40
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(35)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory