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C1qbp
Gene Detail
Symbol

Name
ID
C1qbp
complement component 1, q subcomponent binding protein
MGI:1194505
Synonyms
D11Wsu182e, HABP1, P32
Feature Type
protein coding gene
Genetic Map
Chromosome 11
43.21 cM
Detailed Genetic Map ± 1 cM


Mapping data(8)
Sequence Map
Chr11:70977836-70983026 bp, - strand
From VEGA annotation of GRCm38

  5191 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:31023  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: C1QBP
Gene Tree: C1qbp

Human
homologs
C1QBP, complement component 1, q subcomponent binding protein
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 708
neXtProt AC: NX_Q07021

Human Synonyms: GC1QBP, gC1qR, gC1Q-R, HABP1, p32, SF2p32

Human Chr (Location): 17p13.3; chr17:5432779-5439151 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(22) : Gene trapped(15) Targeted(7)
Genomic Mutations involving C1qbp (1)
 
Mice homozygous for a knock-out allele exhibit embryonic lethality by E11.5 with poor development, small embryo size, pale and anemic organs, poor cellular proliferation and impaired mitochondrial electron transport chain function.
 
Interactions
C1qbp interacts with 68 markers (Mir32, Mir98, Mir137, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (52 annotations)
Process adaptive immune response, apoptotic process, ...
Component cell surface, cytoplasm, ...
Function adrenergic receptor binding, complement component C1q binding, ...
External Resources: FuncBase
Expression
Literature Summary: (6 records)
Data Summary: Results (232)    Tissues (113)    Images (33)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 226
RT-PCR 6
cDNA source data(152)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase c1qbp ; ZFIN c1qbp    NEW 
Molecular
reagents
All nucleic(160) Genomic(7) cDNA(152) Primer pair(1)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000006079 (Evidence)
Ensembl Gene Model ENSMUSG00000018446 (Evidence)
Entrez Gene 12261 (Evidence)
UniGene 30049
DFCI TC1572377
NIA Mouse Gene Index U033012
Consensus CDS Project CCDS24970.1
International Mouse Phenotyping Consortium Status C1qbp
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000006079 VEGA Gene Model | MGI Sequence Detail 5191 C57BL/6J ±  kb
transcript OTTMUST00000013730 VEGA | MGI Sequence Detail 1175 Not Applicable 
polypeptide OTTMUSP00000006368 VEGA | MGI Sequence Detail 279 Not Applicable 

For the selected sequences
All sequences(33) RefSeq(2) UniProt(2)
Polymorphisms
RFLP(1) : SNPs within 2kb(40 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR003428 Mitochondrial glycoprotein
Protein Ontology PR:000004877 complement component 1 Q subcomponent-binding protein, mitochondrial
References
(Earliest) J:46848 Caubin J, et al., Isolation of genomic DNA fragments corresponding to genes modulated in vivo by a transcription factor. Nucleic Acids Res. 1994 Oct 11;22(20):4132-8
(Latest) J:196232 Yagi M, et al., p32/gC1qR is indispensable for fetal development and mitochondrial translation: importance of its RNA-binding ability. Nucleic Acids Res. 2012 Oct;40(19):9717-37
All references(58)
Other
accession IDs
MGD-MRK-36447, MGI:107870, MGI:2143969, MGI:2144060

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory