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Atp2a3
Gene Detail
 Symbol
Name
ID
Atp2a3
ATPase, Ca++ transporting, ubiquitous
MGI:1194503
Synonyms Serca3
Feature Type protein coding gene
Genetic Map
Chromosome 11
45.00 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr11:72961169-72993044 bp, + strand
From VEGA annotation of GRCm38

  31876 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:69131  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: Na(+)/K(+)-transporting ATPase alpha chain
Gene Tree: Atp2a3

Human
homologs
Human Homolog ATP2A3, ATPase, Ca++ transporting, ubiquitous
NCBI Gene ID 489
neXtProt AC  NX_Q93084
Human Synonyms  SERCA3
Human Chr (Location)  17p13.3; chr17:3923869-3964464 (-)  GRCh38
Alleles
and
phenotypes
All alleles(3) : Targeted(3)
 
Homozygous mutation of this gene results in reduced endothelial-dependent relaxation in the aorta.
 
Gene Ontology
(GO)
classifications
All GO classifications: (22 annotations)
Process ATP catabolic process, calcium ion transmembrane transport, ...
Component endoplasmic reticulum, endoplasmic reticulum membrane, ...
Function ATP binding, calcium-transporting ATPase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
cDNA source data(111)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(112) Genomic(1) cDNA(111)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000006323 (Evidence)
Ensembl Gene ModelENSMUSG00000020788 (Evidence)
Entrez Gene53313 (Evidence)
UniGene6306
DFCITC1577006, TC1588255
DoTSDT.101371381, DT.97362372
NIA Mouse Gene IndexU012888
EC3.6.3.8
Consensus CDS ProjectCCDS24991.1, CCDS48842.1, CCDS48843.1
International Mouse Knockout Project StatusAtp2a3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000006323 VEGA Gene Model | MGI Sequence Detail 31876 C57BL/6J ±  kb
transcript OTTMUST00000014354 VEGA | MGI Sequence Detail 4540 Not Applicable 
polypeptide OTTMUSP00000006654 VEGA | MGI Sequence Detail 1020 Not Applicable 

For the selected sequences
All sequences(53) RefSeq(6) UniProt(9)
Polymorphisms SNPs within 2kb(211 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR005782 Calcium-transporting P-type ATPase, subfamily IIA, SERCA-type
InterPro IPR001757 Cation-transporting P-type ATPase
InterPro IPR006068 Cation-transporting P-type ATPase, C-terminal
InterPro IPR004014 Cation-transporting P-type ATPase, N-terminal
InterPro IPR023214 HAD-like domain
InterPro IPR008250 P-type ATPase, A domain
InterPro IPR023299 P-type ATPase, cytoplasmic domain N
InterPro IPR018303 P-type ATPase, phosphorylation site
InterPro IPR023298 P-type ATPase, transmembrane domain
Protein Ontology PR:000004444 sarcoplasmic/endoplasmic reticulum calcium ATPase 3
References (Earliest) J:41924 Slack JP, et al., Ectopic expression of phospholamban in fast-twitch skeletal muscle alters sarcoplasmic reticulum Ca2+ transport and muscle relaxation. J Biol Chem. 1997 Jul 25;272(30):18862-8
(Latest) J:190524 Shalom-Barak T, et al., Placental PPARgamma regulates spatiotemporally diverse genes and a unique metabolic network. Dev Biol. 2012 Dec 1;372(1):143-55
All references(44)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory