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Ablim1
Gene Detail
Symbol

Name
ID
Ablim1
actin-binding LIM protein 1
MGI:1194500
Synonyms
2210411C18Rik, 2610209L21Rik, 4833406P10Rik, 9330196J19Rik, abLIM-L, abLIM-M, abLIM-S, Limab1, mKIAA0059
Feature Type
protein coding gene
Genetic Map
Chromosome 19
52.09 cM
Detailed Genetic Map ± 1 cM


Mapping data(6)
Sequence Map
Chr19:57032733-57314919 bp, - strand
From VEGA annotation of GRCm38

  282187 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:40994  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Ablim1

Human
homologs
Human Homolog ABLIM1, actin binding LIM protein 1
NCBI Gene ID 3983
neXtProt AC  NX_O14639
Human Synonyms  ABLIM, abLIM-1, LIMAB1, LIMATIN
Human Chr (Location)  10q25; chr10:114431110-114768609 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(10) : Gene trapped(5) Targeted(5)
Incidental mutations (data from Mutagenetix , APF )
 
Mutant mice lacking the retina-specific isoform are healthy, fertile, and show no defects in retinal development or retinofugal projections.
 
Interactions
Ablim1 interacts with 382 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (15 annotations)
Process axon guidance, cilium assembly, ...
Component actin cytoskeleton, cytoplasm, ...
Function actin binding, metal ion binding, ...
External Resources: FuncBase
Expression
Literature Summary: (11 records)
Data Summary: Results (73)    Tissues (49)    Images (8)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 52
RT-PCR 21
cDNA source data(18)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(26) Genomic(1) cDNA(22) Primer pair(2) Other(1)
Microarray probesets(7)
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016380 VEGA Gene Model | MGI Sequence Detail 282187 C57BL/6J ±  kb
transcript OTTMUST00000039424 VEGA | MGI Sequence Detail 7152 Not Applicable 
polypeptide OTTMUSP00000017615 VEGA | MGI Sequence Detail 861 Not Applicable 

For the selected sequences
All sequences(209) RefSeq(50) UniProt(33)
Polymorphisms
RFLP(1) : SNPs within 2kb(4126 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR003128 Villin headpiece
InterPro IPR001781 Zinc finger, LIM-type
Protein Ontology PR:000003584 actin-binding LIM protein 1
References
(Earliest) J:40509 Kim AC, et al., Limatin (LIMAB1), an actin-binding LIM protein, maps to mouse chromosome 19 and human chromosome 10q25, a region frequently deleted in human cancers. Genomics. 1997 Dec 1;46(2):291-3
(Latest) J:193447 Cao J, et al., miR-129-3p controls cilia assembly by regulating CP110 and actin dynamics. Nat Cell Biol. 2012 Jul;14(7):697-706
All references(49)
Other
accession IDs
MGI:1917386, MGI:1919728, MGI:2147671, MGI:2147702, MGI:2147721, MGI:2442818, MGI:2442960

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory