Ablim1
Gene Detail

Symbol Name ID

Ablim1 actin-binding LIM protein 1 MGI:1194500

Synonyms

2210411C18Rik, 2610209L21Rik, 4833406P10Rik, 9330196J19Rik, abLIM-L, abLIM-M, abLIM-S, Limab1, mKIAA0059

Feature Type

protein coding gene

Genetic Map

Chromosome 19

52.09 cM
Detailed Genetic Map ± 1 cM


Mapping data(6)

Sequence Map

Chr19:57032733-57314919 bp, - strand From VEGA annotation of GRCm38   282187 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:40994  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Ablim1

Human homologs

Human Homolog		ABLIM1, actin binding LIM protein 1
NCBI Gene ID		3983
neXtProt AC		NX_O14639
Human Synonyms		ABLIM, abLIM-1, LIMAB1, LIMATIN
Human Chr (Location)		10q25; chr10:116190869-116444414 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(10) : Targeted(5) Gene trapped(5)
 

Mutant mice lacking the retina-specific isoform are healthy, fertile, and show no defects in retinal development or retinofugal projections.

 

Gene Ontology (GO) classifications

All GO classifications: (10 annotations)

Process	axon guidance, cytoskeleton organization, ...
Component	actin cytoskeleton, cytoplasm, ...
Function	actin binding, metal ion binding, ...

External Resources: FuncBase

Expression

Literature Summary: (11 records)
Data Summary: Results (80)    Tissues (53)    Images (8)
Theiler Stages: 2, 3, 4, 5, 16, 17, 19, 21, 22, 23, 26, 28

Assay Type	Results
RNA in situ	52
RT-PCR	28

cDNA source data(17)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(25) Genomic(1) cDNA(21) Primer pair(2) Other(1)
Microarray probesets(7)

Other database links

VEGA Gene Model	OTTMUSG00000016380 (Evidence)
Ensembl Gene Model	ENSMUSG00000025085 (Evidence)
Entrez Gene	226251 (Evidence)
DFCI	TC1579336, TC1590006, TC1591520, TC1599327, TC1602925, TC1605728, TC1615008, TC1640562, TC1762194
DoTS	DT.101282899, DT.101310883, DT.101382883, DT.101382884, DT.101382886, DT.110861660, DT.490371, DT.55115676, DT.55241894, DT.91329356, DT.97351015, DT.97373120, DT.97404398
NIA Mouse Gene Index	U039175
Consensus CDS Project	CCDS38027.1, CCDS50478.1, CCDS50479.1
International Mouse Knockout Project Status	Ablim1

Sequences

Length	Strain/Species
genomic	OTTMUSG00000016380	VEGA Gene Model | MGI Sequence Detail	282187	C57BL/6J
transcript	OTTMUST00000039424	VEGA | MGI Sequence Detail	7152	Not Applicable
polypeptide	OTTMUSP00000017615	VEGA | MGI Sequence Detail	861	Not Applicable

All sequences(147) RefSeq(6) UniProt(17)

Polymorphisms

RFLP(1) : SNPs(1570 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR003128	Villin headpiece
InterPro	IPR001781	Zinc finger, LIM-type
Protein Ontology	PR:000003584	actin-binding LIM protein 1

References

(Earliest) J:40509 Kim AC, et al., Limatin (LIMAB1), an actin-binding LIM protein, maps to mouse chromosome 19 and human chromosome 10q25, a region frequently deleted in human cancers. Genomics. 1997 Dec 1;46(2):291-3
(Latest) J:171293 Campbell GR, et al., Transcription factors expressed in olfactory bulb local progenitor cells revealed by genome-wide transcriptome profiling. Mol Cell Neurosci. 2011 Feb;46(2):548-61
All references(47)

Other accession IDs

MGI:1917386, MGI:1919728, MGI:2147671, MGI:2147702, MGI:2147721, MGI:2442818, MGI:2442960