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Ablim1 Gene Detail
Summary
  • Symbol
    Ablim1
  • Name
    actin-binding LIM protein 1
  • Synonyms
    2210411C18Rik, 2610209L21Rik, 4833406P10Rik, 9330196J19Rik, abLIM-L, abLIM-M, abLIM-S, Limab1, mKIAA0059
  • Feature Type
    protein coding gene
  • IDs
    MGI:1194500
    NCBI Gene: 226251
  • Gene Overview
    MyGene.info: ABLIM1
Location & Maps
more
  • Sequence Map
    Chr19:57032733-57314919 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      282187 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 19, 52.09 cM
  • Mapping Data
    6 experiments
Homology
more
  • Human Ortholog
    ABLIM1, actin binding LIM protein 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    ABLIM1, actin binding LIM protein 1
    Orthology source: HomoloGene
  • Synonyms
    ABLIM, abLIM-1, LIMAB1, LIMATIN
  • Links
    NCBI Gene ID: 3983
    neXtProt AC: NX_O14639

  • Chr Location
    10q25; chr10:114431110-114821643 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    6 phenotype references
Mutant mice lacking the retina-specific isoform are healthy, fertile, and show no defects in retinal development or retinofugal projections.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016380 VEGA Gene Model | MGI Sequence Detail 282187 C57BL/6J ±  kb
transcript OTTMUST00000039424 VEGA | MGI Sequence Detail 7152 Not Applicable  
polypeptide OTTMUSP00000017615 VEGA | MGI Sequence Detail 861 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    4122 from dbSNP Build 142
  • RFLP
Protein
Information
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  • UniProt
    17 Sequences
  • InterPro Domains
    IPR028448 Actin-binding LIM protein 1
    IPR032402 Putative adherens-junction anchoring domain
    IPR003128 Villin headpiece
    IPR001781 Zinc finger, LIM-type
Molecular
Reagents
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  • All nucleic 26
    Genomic 1
    cDNA 22
    Primer pair 2
    Other 1

    Microarray probesets 7
Other
Accession IDs
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MGI:1917386, MGI:1919728, MGI:2147671, MGI:2147702, MGI:2147721, MGI:2442818, MGI:2442960
References
more
  • Summaries
    All 44
    Developmental Gene Expression 11
    Gene Ontology 8
    Phenotypes 6
  • Earliest
    J:40509 Kim AC, et al., Limatin (LIMAB1), an actin-binding LIM protein, maps to mouse chromosome 19 and human chromosome 10q25, a region frequently deleted in human cancers. Genomics. 1997 Dec 1;46(2):291-3
  • Latest
    J:193447 Cao J, et al., miR-129-3p controls cilia assembly by regulating CP110 and actin dynamics. Nat Cell Biol. 2012 Jul;14(7):697-706

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/22/2016
MGI 6.04
The Jackson Laboratory