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Ablim1
Gene Detail
 Symbol
Name
ID
Ablim1
actin-binding LIM protein 1
MGI:1194500
Synonyms 2210411C18Rik, 2610209L21Rik, 4833406P10Rik, 9330196J19Rik, abLIM-L, abLIM-M, abLIM-S, Limab1, mKIAA0059
Feature Type protein coding gene
Genetic Map
Chromosome 19
52.09 cM
Detailed Genetic Map ± 1 cM


Mapping data(6)
Sequence Map
Chr19:57032733-57314919 bp, - strand
From VEGA annotation of GRCm38

  282187 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:40994  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Ablim1

Human
homologs
Human Homolog ABLIM1, actin binding LIM protein 1
NCBI Gene ID 3983
neXtProt AC  NX_O14639
Human Synonyms  ABLIM, abLIM-1, LIMAB1, LIMATIN
Human Chr (Location)  10q25; chr10:114431110-114768609 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(10) : Gene trapped(5) Targeted(5)
Incidental mutations (data from Mutagenetix , APF )
 
Mutant mice lacking the retina-specific isoform are healthy, fertile, and show no defects in retinal development or retinofugal projections.
 
Interactions
Ablim1 interacts with 382 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process axon guidance, cilium assembly, ...
Component actin cytoskeleton, cytoplasm, ...
Function actin binding, metal ion binding, ...
External Resources: FuncBase
Expression
Literature Summary: (11 records)
Data Summary: Results (73)    Tissues (49)    Images (8)
Theiler Stages: 2, 3, 4, 5, 16, 17, 19, 21, 22, 23, 26, 27, 28
Assay TypeResults
RNA in situ 52
RT-PCR 21
cDNA source data(18)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(26) Genomic(1) cDNA(22) Primer pair(2) Other(1)
Microarray probesets(7)
Other database
links
VEGA Gene ModelOTTMUSG00000016380 (Evidence)
Ensembl Gene ModelENSMUSG00000025085 (Evidence)
Entrez Gene226251 (Evidence)
DFCITC1579336, TC1590006, TC1591520, TC1599327, TC1602925, TC1605728, TC1615008, TC1640562, TC1762194
DoTSDT.101282899, DT.101310883, DT.101382883, DT.101382884, DT.101382886, DT.110861660, DT.490371, DT.55115676, DT.55241894, DT.91329356, DT.94128256, DT.97351015, DT.97373120, DT.97404398
NIA Mouse Gene IndexU039175
Consensus CDS ProjectCCDS38027.1, CCDS50478.1, CCDS50479.1, CCDS70963.1, CCDS70964.1
International Mouse Knockout Project StatusAblim1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016380 VEGA Gene Model | MGI Sequence Detail 282187 C57BL/6J ±  kb
transcript OTTMUST00000039424 VEGA | MGI Sequence Detail 7152 Not Applicable 
polypeptide OTTMUSP00000017615 VEGA | MGI Sequence Detail 861 Not Applicable 

For the selected sequences
All sequences(193) RefSeq(50) UniProt(17)
Polymorphisms RFLP(1) : SNPs within 2kb(4126 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR003128 Villin headpiece
InterPro IPR001781 Zinc finger, LIM-type
Protein Ontology PR:000003584 actin-binding LIM protein 1
References (Earliest) J:40509 Kim AC, et al., Limatin (LIMAB1), an actin-binding LIM protein, maps to mouse chromosome 19 and human chromosome 10q25, a region frequently deleted in human cancers. Genomics. 1997 Dec 1;46(2):291-3
(Latest) J:193447 Cao J, et al., miR-129-3p controls cilia assembly by regulating CP110 and actin dynamics. Nat Cell Biol. 2012 Jul;14(7):697-706
All references(48)
Other
accession IDs
MGI:1917386, MGI:1919728, MGI:2147671, MGI:2147702, MGI:2147721, MGI:2442818, MGI:2442960

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory