Sepw1
Gene Detail

Symbol Name ID

Sepw1 selenoprotein W, muscle 1 MGI:1100878

Feature Type

protein coding gene

Genetic Map

Chromosome 7

8.62 cM, cytoband A2
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr7:15917208-15922402 bp, - strand From VEGA annotation of GRCm38   5195 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:2263  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Sepw1

Human homologs

Human Homolog		SEPW1, selenoprotein W, 1
NCBI Gene ID		6415
neXtProt AC		NX_P63302
Human Synonyms		selW
Human Chr (Location)		19q13.3; chr19:48281842-48287939 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(9) : Targeted(3) Gene trapped(6)

Gene Ontology (GO) classifications

All GO classifications: (7 annotations)

Process	cell redox homeostasis, oxidation-reduction process
Component	cytoplasm, plasma membrane
Function	antioxidant activity, oxidoreductase activity, ...

External Resources: FuncBase

Expression

Literature Summary: (3 records)
Data Summary: Results (26)    Tissues (5)    Images (15)
Theiler Stages: 23

Assay Type	Results
RNA in situ	26

cDNA source data(285)
External Resources: Allen Institute   GENSAT   GEO   ArrayExpress

Molecular reagents

All nucleic(288) Genomic(3) cDNA(285)
Microarray probesets(4)

Other database links

VEGA Gene Model	OTTMUSG00000021063 (Evidence)
Ensembl Gene Model	ENSMUSG00000041571 (Evidence)
Entrez Gene	20364 (Evidence)
UniGene	42829
DFCI	TC1572150, TC1765032
DoTS	DT.101309272, DT.537155, DT.94306742
NIA Mouse Gene Index	U028172
PDB	2NPB
Consensus CDS Project	CCDS39778.1
International Mouse Knockout Project Status	Sepw1

Sequences

Length	Strain/Species
genomic	OTTMUSG00000021063	VEGA Gene Model | MGI Sequence Detail	5195	C57BL/6J
transcript	OTTMUST00000049826	VEGA | MGI Sequence Detail	736	Not Applicable
polypeptide	OTTMUSP00000023148	VEGA | MGI Sequence Detail	88	Not Applicable

All sequences(25) RefSeq(2) UniProt(1)

Polymorphisms

SNPs(11 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR011893	Selenoprotein, Rdx type
InterPro	IPR012336	Thioredoxin-like fold
Protein Ontology	PR:000014662	selenoprotein W

References

(Earliest) J:41818 Gu QP, et al., Conserved features of selenocysteine insertion sequence (SECIS) elements in selenoprotein W cDNAs from five species. Gene. 1997 Jul 9;193(2):187-96
(Latest) J:192903 Park YH, et al., Selenoprotein W promotes cell cycle recovery from G2 arrest through the activation of CDC25B. Biochim Biophys Acta. 2012 Dec;1823(12):2217-26
All references(37)