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Sepw1
Gene Detail
Symbol

Name
ID
Sepw1
selenoprotein W, muscle 1
MGI:1100878
Feature Type
protein coding gene
Genetic Map
Chromosome 7
8.62 cM, cytoband A2
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr7:15917208-15922371 bp, - strand
From NCBI annotation of GRCm38

  5164 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:2263  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Sepw1

Human
homologs
Human Homolog SEPW1, selenoprotein W, 1
NCBI Gene ID 6415
neXtProt AC  NX_P63302
Human Synonyms  selW
Human Chr (Location)  19q13.3; chr19:47778585-47784682 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(9) : Gene trapped(6) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Sepw1 interacts with 43 markers (Mir30a, Mir30d, Mir30e, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Process cell redox homeostasis, oxidation-reduction process
Component cytoplasm, plasma membrane
Function antioxidant activity, oxidoreductase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (26)    Tissues (5)    Images (15)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 26
cDNA source data(285)
External Resources: Allen Institute   GENSAT   GEO   Expression Atlas
Molecular
reagents
All nucleic(288) Genomic(3) cDNA(285)
Microarray probesets(4)
Other database
links
Ensembl Gene ModelENSMUSG00000041571 (Evidence)
Entrez Gene20364 (Evidence)
UniGene42829
DFCITC1572150, TC1765032
DoTSDT.94306742, DT.101309272, DT.537155
NIA Mouse Gene IndexU028172
PDB2NPB
Consensus CDS ProjectCCDS39778.1
International Mouse Knockout Project StatusSepw1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 20364 NCBI Gene Model | MGI Sequence Detail 5164 C57BL/6J ±  kb
transcript NM_009156 RefSeq | MGI Sequence Detail 722 C57BL/6 
polypeptide P63300 UniProt | EBI | MGI Sequence Detail 88 Not Applicable 

For the selected sequences
All sequences(22) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(17 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR011893 Selenoprotein, Rdx type
InterPro IPR012336 Thioredoxin-like fold
Protein Ontology PR:000014662 selenoprotein W
Graphical View of Protein Domain Structure
References
(Earliest) J:41818 Gu QP, et al., Conserved features of selenocysteine insertion sequence (SECIS) elements in selenoprotein W cDNAs from five species. Gene. 1997 Jul 9;193(2):187-96
(Latest) J:210222 Hupe M, et al., Evaluation of TRAP-sequencing technology with a versatile conditional mouse model. Nucleic Acids Res. 2014 Jan;42(2):e14
All references(39)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory