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Mid1
Gene Detail
Symbol

Name
ID
Mid1
midline 1
MGI:1100537
Synonyms
61B3-R, DXHXS1141, Fxy, Trim18
Feature Type
protein coding gene
Genetic Map
Chromosome X
79.19 cM
Detailed Genetic Map ± 1 cM


Mapping data(11)
Sequence Map
ChrX:169685199-169990798 bp, + strand
From VEGA annotation of GRCm38

  305600 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
Protein SuperFamily: midline
Gene Tree: Mid1
Mutations,
alleles, and
phenotypes
All mutations/alleles(8) : Gene trapped(5) Targeted(3)
 
Mice homozygous or hemizygous for disruptions in this gene have a normal phenotype.
 
Human Diseases Modeled Using Mouse Mid1 (2)    Alleles Annotated to Human Diseases(2)   
Interactions
Mid1 interacts with 124 markers (Mir10a, Mir10b, Mir15a, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (15 records)
Data Summary: Results (176)    Tissues (96)    Images (29)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 145
Northern blot 9
RT-PCR 22
cDNA source data(14)
External Resources: Allen Institute   Expression Atlas
Molecular
reagents
All nucleic(24) Genomic(3) cDNA(17) Primer pair(4)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000019599 (Evidence)
Ensembl Gene ModelENSMUSG00000035299 (Evidence)
EC6.3.2.-
International Mouse Knockout Project StatusMid1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000019599 VEGA Gene Model | MGI Sequence Detail 305600 C57BL/6J ±  kb
transcript OTTMUST00000046821 VEGA | MGI Sequence Detail 3860 Not Applicable 
polypeptide OTTMUSP00000021178 VEGA | MGI Sequence Detail 680 Not Applicable 

For the selected sequences
All sequences(68) UniProt(11)
Polymorphisms
RFLP(3) : SNPs within 2kb(917 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001870 B30.2/SPRY domain
InterPro IPR003649 B-box, C-terminal
InterPro IPR003879 Butyrophylin-like
InterPro IPR013320 Concanavalin A-like lectin/glucanase, subgroup
InterPro IPR017903 COS domain
InterPro IPR003961 Fibronectin, type III
InterPro IPR013783 Immunoglobulin-like fold
InterPro IPR003877 SPla/RYanodine receptor SPRY
InterPro IPR006574 SPRY-associated
InterPro IPR000315 Zinc finger, B-box
InterPro IPR013083 Zinc finger, RING/FYVE/PHD-type
InterPro IPR001841 Zinc finger, RING-type
InterPro IPR017907 Zinc finger, RING-type, conserved site
Protein Ontology PR:000010406 midline-1
References
(Earliest) J:43704 Palmer S, et al., A gene spans the pseudoautosomal boundary in mice. Proc Natl Acad Sci U S A. 1997 Oct 28;94(22):12030-5
(Latest) J:206774 Wolstenholme JT, et al., Sexual differentiation in the developing mouse brain: contributions of sex chromosome genes. Genes Brain Behav. 2013 Mar;12(2):166-80
All references(44)
Disease annotation references (1)
Other
accession IDs
MGI:1345953

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory