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Slc7a3
Gene Detail
 Symbol
Name
ID
Slc7a3
solute carrier family 7 (cationic amino acid transporter, y+ system), member 3
MGI:1100521
Synonyms Atrc3, Cat3, SLC7A1, SLC7A2
Feature Type protein coding gene
Genetic Map
Chromosome X
43.72 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
ChrX:101079210-101086020 bp, - strand
From VEGA annotation of GRCm38

  6811 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:56382  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 2 zebrafish

Protein SuperFamily: amino acid transporter
Gene Tree: Slc7a3

Human
homologs
Human Homolog SLC7A3, solute carrier family 7 (cationic amino acid transporter, y+ system), member 3
NCBI Gene ID 84889
neXtProt AC  NX_Q8WY07
Human Synonyms  ATRC3, CAT3, CAT-3
Human Chr (Location)  Xq13.1; chrX:70925579-70931125 (-)  GRCh38
Alleles
and
phenotypes
All alleles(14) : Targeted(1) Gene trapped(13)
Gene Ontology
(GO)
classifications
All GO classifications: (25 annotations)
Process amino acid transmembrane transport, amino acid transport, ...
Component integral component of membrane, integral component of plasma membrane, ...
Function amino acid transmembrane transporter activity, arginine transmembrane transporter activity, ...
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (122)    Tissues (36)    Images (28)
Theiler Stages: 2, 3, 10, 12, 21, 23, 25, 28
Assay TypeResults
RNA in situ 68
Northern blot 1
RT-PCR 53
cDNA source data(28)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(32) cDNA(28) Primer pair(4)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000018298 (Evidence)
Ensembl Gene ModelENSMUSG00000031297 (Evidence)
Entrez Gene11989 (Evidence)
UniGene5140
DFCITC1580062
DoTSDT.111037241, DT.50316230, DT.94227066
NIA Mouse Gene IndexU039569
Consensus CDS ProjectCCDS30309.1
International Mouse Knockout Project StatusSlc7a3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000018298 VEGA Gene Model | MGI Sequence Detail 6811 C57BL/6J ±  kb
transcript OTTMUST00000044208 VEGA | MGI Sequence Detail 2371 Not Applicable 
polypeptide OTTMUSP00000019875 VEGA | MGI Sequence Detail 618 Not Applicable 

For the selected sequences
All sequences(45) RefSeq(10) UniProt(2)
Polymorphisms SNPs within 2kb(37 from dbSNP Build 137)    SNPs within 2kb including multiple locations(39)
Protein-related
information
ResourceIDDescription
InterPro IPR002293 Amino acid/polyamine transporter I
InterPro IPR004755 Cationic amino acid transport permease
Protein Ontology PR:000015199 cationic amino acid transporter 3
References (Earliest) J:43574 Ito K, et al., A new member of the cationic amino acid transporter family is preferentially expressed in adult mouse brain. J Biol Chem. 1997 Oct 17;272(42):26780-6
(Latest) J:174767 Tang F, et al., Deterministic and stochastic allele specific gene expression in single mouse blastomeres. PLoS One. 2011;6(6):e21208
All references(34)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory