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Vps4b Gene Detail
Summary
  • Symbol
    Vps4b
  • Name
    vacuolar protein sorting 4B
  • Synonyms
    8030489C12Rik, Skd1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1100499
    NCBI Gene: 20479
  • Gene Overview
    MyGene.info: VPS4B
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:106770788-106796725 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 50.10 cM, cytoband D
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    139 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1100499
protein coding gene Chr1:106764071-106796728 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016373
protein coding gene Chr1:108946996-108979715 (-)
A/J MGP_AJ_G0016357
protein coding gene Chr1:105126729-105159453 (-)
AKR/J MGP_AKRJ_G0016317
protein coding gene Chr1:107998983-108031709 (-)
BALB/cJ MGP_BALBcJ_G0016313
protein coding gene Chr1:105223306-105256031 (-)
C3H/HeJ MGP_C3HHeJ_G0016140
protein coding gene Chr1:108452050-108484773 (-)
C57BL/6NJ MGP_C57BL6NJ_G0016772
protein coding gene Chr1:113085496-113119546 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014490
protein coding gene Chr1:99431946-99466206 (-)
CAST/EiJ MGP_CASTEiJ_G0015722
protein coding gene Chr1:107376361-107408436 (-)
CBA/J MGP_CBAJ_G0016113
protein coding gene Chr1:116955645-116989259 (-)
DBA/2J MGP_DBA2J_G0016218
protein coding gene Chr1:104195943-104228653 (-)
FVB/NJ MGP_FVBNJ_G0016219
protein coding gene Chr1:103127856-103160557 (-)
LP/J MGP_LPJ_G0016292
protein coding gene Chr1:110182864-110217270 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016245
protein coding gene Chr1:121362960-121396935 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0016811
protein coding gene Chr1:108089740-108122708 (-)
PWK/PhJ MGP_PWKPhJ_G0015510
protein coding gene Chr1:103217466-103251171 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015295
protein coding gene Chr1:106744814-106777906 (-)
WSB/EiJ MGP_WSBEiJ_G0015785
protein coding gene Chr1:107917309-107950103 (-)



Homology
more
  • Human Ortholog
    VPS4B, vacuolar protein sorting 4 homolog B
  • Vertebrate Orthologs
    10
  • Human Ortholog
    VPS4B, vacuolar protein sorting 4 homolog B
    Orthology source: HomoloGene, HGNC
  • Synonyms
    MIG1, SKD1, SKD1B, VPS4-2
  • Links
    NCBI Gene ID: 9525
    neXtProt AC: NX_O75351
    UniProt: O75351

  • Chr Location
    18q21.33; chr18:63389190-63422519 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    2
  • Gene trapped
    2
  • Radiation induced
    1
  • Genomic Mutations
    3 involving Vps4b
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 20479 NCBI Gene Model | MGI Sequence Detail 25938 C57BL/6J ±  kb
transcript NM_009190 RefSeq | MGI Sequence Detail 3272 C57BL/6  
polypeptide P46467 UniProt | EBI | MGI Sequence Detail 444 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 14
    cDNA 14

    Microarray probesets 6
Other
Accession IDs
less
MGI:2442405
References
more
  • Summaries
    All 41
    Gene Ontology 13
    Phenotypes 6
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:201479 Srivastava U, et al., Differences in health status affect susceptibility and mapping of genetic loci for atherosclerosis (fatty streak) in inbred mice. Arterioscler Thromb Vasc Biol. 2012 Oct;32(10):2380-6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory