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Vps4b Gene Detail
Summary
  • Symbol
    Vps4b
  • Name
    vacuolar protein sorting 4B
  • Synonyms
    8030489C12Rik, Skd1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1100499
    NCBI Gene: 20479
  • Gene Overview
    MyGene.info: VPS4B
Location & Maps
more
  • Sequence Map
    Chr1:106764071-106796728 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      32658 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    VPS4B, vacuolar protein sorting 4 homolog B
  • Vertebrate Orthologs
    10
  • Human Ortholog
    VPS4B, vacuolar protein sorting 4 homolog B
    Orthology source: HGNC, HomoloGene
  • Synonyms
    MIG1, SKD1, SKD1B, VPS4-2
  • Links
    NCBI Gene ID: 9525
    neXtProt AC: NX_O75351

  • Chr Location
    18q21.33; chr18:63389190-63422519 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    2
  • Gene trapped
    2
  • Radiation induced
    1
  • Genomic Mutations
    3 involving Vps4b
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000021646 VEGA Gene Model | MGI Sequence Detail 32658 C57BL/6J ±  kb
transcript OTTMUST00000051390 VEGA | MGI Sequence Detail 4539 Not Applicable  
polypeptide OTTMUSP00000024169 VEGA | MGI Sequence Detail 444 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    191 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 13
    cDNA 13

    Microarray probesets 6
Other
Accession IDs
less
MGI:2442405
References
more
  • Summaries
    All 35
    Gene Ontology 12
    Phenotypes 6
  • Earliest
    J:20181 Perier F, et al., Identification of a novel mammalian member of the NSF/CDC48p/Pas1p/TBP-1 family through heterologous expression in yeast. FEBS Lett. 1994 Sep 5;351(2):286-90
  • Latest
    J:227378 Sahu R, et al., Microautophagy of cytosolic proteins by late endosomes. Dev Cell. 2011 Jan 18;20(1):131-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/26/2016
MGI 6.03
The Jackson Laboratory