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Skiv2l
Gene Detail
 Symbol
Name
ID
Skiv2l
superkiller viralicidic activity 2-like (S. cerevisiae)
MGI:1099835
Synonyms 4930534J06Rik, Ski2w
Feature Type protein coding gene
Genetic Map
Chromosome 17
18.39 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr17:34839228-34850210 bp, - strand
From VEGA annotation of GRCm38

  10983 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:123971  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 zebrafish

Protein SuperFamily: antiviral helicase, SKI2 type
Gene Tree: Skiv2l

Human
homologs
Human Homolog SKIV2L, superkiller viralicidic activity 2-like (S. cerevisiae)
NCBI Gene ID 6499
neXtProt AC  NX_Q15477
Human Synonyms  170A, DDX13, HLP, SKI2, SKI2W, SKIV2, THES2
Human Chr (Location)  6p21; chr6:31958804-31969755 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human SKIV2L
Alleles
and
phenotypes
All alleles(4) : Targeted(3) Transgenic(1)
 
Mice homozygous for a transgenic gene disruption exhibit embryonic lethality at E6.
 
Gene Ontology
(GO)
classifications
All GO classifications: (6 annotations)
Component nucleus, Ski complex
Function ATP binding, helicase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (1)    Tissues (1)    Images (1)
Theiler Stages: 23
Assay TypeResults
RNA in situ 1
cDNA source data(118)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(119) Genomic(1) cDNA(118)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000037261 (Evidence)
Ensembl Gene ModelENSMUSG00000040356 (Evidence)
Entrez Gene108077 (Evidence)
UniGene18845
DFCITC1572899, TC1595793, TC1608550, TC1714391, TC1736867
DoTSDT.101231748, DT.101403119, DT.110559173, DT.491690, DT.94155704
NIA Mouse Gene IndexU037724
Consensus CDS ProjectCCDS28661.1
International Mouse Knockout Project StatusSkiv2l
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000037261 VEGA Gene Model | MGI Sequence Detail 10983 C57BL/6J ±  kb
transcript OTTMUST00000096090 VEGA | MGI Sequence Detail 3951 Not Applicable 
polypeptide OTTMUSP00000053648 VEGA | MGI Sequence Detail 1244 Not Applicable 

For the selected sequences
All sequences(99) RefSeq(7) UniProt(8)
Polymorphisms SNPs within 2kb(83 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR011545 DNA/RNA helicase, DEAD/DEAH box type, N-terminal
InterPro IPR012961 DSH, C-terminal
InterPro IPR001650 Helicase, C-terminal
InterPro IPR014001 Helicase, superfamily 1/2, ATP-binding domain
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR016438 RNA helicase, ATP-dependent, SK12/DOB1
InterPro IPR025696 rRNA-processing arch domain
Protein Ontology PR:000014907 helicase SKI2W
References (Earliest) J:43702 Gee S, et al., Cloning of mDEAH9, a putative RNA helicase and mammalian homologue of Saccharomyces cerevisiae splicing factor Prp43. Proc Natl Acad Sci U S A. 1997 Oct 28;94(22):11803-7
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(35)
Other
accession IDs
MGI:2147055, MGI:2148488, MGI:2442955

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory