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She Gene Detail
Summary
  • Symbol
    She
  • Name
    src homology 2 domain-containing transforming protein E
  • Feature Type
    protein coding gene
  • IDs
    MGI:1099462
    NCBI Gene: 214547
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:89831370-89858834 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 39.19 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    67 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1099462
protein coding gene Chr3:89831370-89858846 (+)
129S1/SvImJ MGP_129S1SvImJ_G0027447
protein coding gene Chr3:90068341-90096755 (+)
A/J MGP_AJ_G0027411
protein coding gene Chr3:87087670-87115074 (+)
AKR/J MGP_AKRJ_G0027375
protein coding gene Chr3:89213052-89240167 (+)
BALB/cJ MGP_BALBcJ_G0027420
protein coding gene Chr3:87058354-87086362 (+)
C3H/HeJ MGP_C3HHeJ_G0027162
protein coding gene Chr3:89395517-89422741 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027866
protein coding gene Chr3:93456897-93484801 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025218
protein coding gene Chr3:82576121-82605525 (+)
CAST/EiJ MGP_CASTEiJ_G0026608
protein coding gene Chr3:89772318-89804869 (+)
CBA/J MGP_CBAJ_G0027136
protein coding gene Chr3:96687978-96715052 (+)
DBA/2J MGP_DBA2J_G0027274
protein coding gene Chr3:86466778-86493899 (+)
FVB/NJ MGP_FVBNJ_G0027242
protein coding gene Chr3:84800658-84829844 (+)
LP/J MGP_LPJ_G0027383
protein coding gene Chr3:91141996-91172710 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0027262
protein coding gene Chr3:102868615-102898535 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027925
protein coding gene Chr3:88952738-88980286 (+)
PWK/PhJ MGP_PWKPhJ_G0026342
protein coding gene Chr3:86351208-86381251 (+)
SPRET/EiJ MGP_SPRETEiJ_G0026161
protein coding gene Chr3:88138761-88170221 (+)
WSB/EiJ MGP_WSBEiJ_G0026690
protein coding gene Chr3:89354285-89382063 (+)



Homology
more
  • Human Ortholog
    SHE, Src homology 2 domain containing E
  • Vertebrate Orthologs
    9
  • Human Ortholog
    SHE, Src homology 2 domain containing E
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 126669
    neXtProt AC: NX_Q5VZ18
    UniProt: Q5VZ18

  • Chr Location
    1q21.3; chr1:154469637-154502059 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 18186
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed
  • HCOP
    human homology predictions: SHE
  • Gene Tree
    She
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000046280 Ensembl Gene Model | MGI Sequence Detail 27465 C57BL/6J ±  kb
transcript ENSMUST00000050401 Ensembl | MGI Sequence Detail 5733 Not Applicable  
polypeptide ENSMUSP00000059658 Ensembl | MGI Sequence Detail 492 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 13
    cDNA 13

    Microarray probesets 4
References
more
  • Summaries
    All 30
    Developmental Gene Expression 2
    Diseases 1
    Gene Ontology 2
    Phenotypes 9
  • Earliest
    J:43082 Oda T, et al., Identification and characterization of two novel SH2 domain-containing proteins from a yeast two hybrid screen with the ABL tyrosine kinase. Oncogene. 1997 Sep;15(11):1255-62
  • Latest
    J:188649 Takase H, et al., Genome-wide identification of endothelial cell-enriched genes in the mouse embryo. Blood. 2012 Jul 26;120(4):914-23

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory