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Rbm3
Gene Detail
Symbol

Name
ID
Rbm3
RNA binding motif protein 3
MGI:1099460
Synonyms
2600016C11Rik
Feature Type
protein coding gene
Genetic Map
Chromosome X
3.68 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
ChrX:8138975-8145880 bp, - strand
From VEGA annotation of GRCm38

  6906 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:31404  Vertebrate Homology Class
1 human; 2 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Gene Tree: Rbm3

Human
homologs
Human Homolog RBM3, RNA binding motif (RNP1, RRM) protein 3
NCBI Gene ID 5935
neXtProt AC  NX_P98179
Human Synonyms  IS1-RNPL, RNPL
Human Chr (Location)  Xp11.2; chrX:48574353-48581165 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(22) : Gene trapped(17) Targeted(5)
 
Mice homozygous for a knock-out allele exhibit decreased cell proliferation in mouse embryonic fibroblasts.
 
Phenotype Images(1)
Interactions
Rbm3 interacts with 281 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (16 annotations)
Process positive regulation of translation, production of miRNAs involved in gene silencing by miRNA, ...
Component cell projection, cytoplasm, ...
Function nucleic acid binding, nucleotide binding, ...
External Resources: FuncBase
Expression
Literature Summary: (6 records)
Data Summary: Results (69)    Tissues (52)    Images (9)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 63
RT-PCR 6
cDNA source data(21)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(30) Genomic(1) cDNA(25) Primer pair(3) Other(1)
Microarray probesets(7)
Other database
links
VEGA Gene ModelOTTMUSG00000018091 (Evidence)
Ensembl Gene ModelENSMUSG00000031167 (Evidence)
Entrez Gene19652 (Evidence)
DoTSDT.101328963, DT.101330747, DT.111036501, DT.537044, DT.60107766, DT.94397334, DT.97398883
Consensus CDS ProjectCCDS29987.1, CCDS52988.1
International Mouse Knockout Project StatusRbm3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000018091 VEGA Gene Model | MGI Sequence Detail 6906 C57BL/6J ±  kb
transcript OTTMUST00000043733 VEGA | MGI Sequence Detail 2792 Not Applicable 
polypeptide OTTMUSP00000019636 VEGA | MGI Sequence Detail 154 Not Applicable 

For the selected sequences
All sequences(93) RefSeq(10) UniProt(9)
Polymorphisms
RFLP(1) : SNPs within 2kb(65 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR012677 Nucleotide-binding, alpha-beta plait
InterPro IPR000504 RNA recognition motif domain
Protein Ontology PR:000029711 RNA-binding protein 3
References
(Earliest) J:43904 Derry JM, et al., RBM3, a novel human gene in Xp11.23 with a putative RNA-binding domain. Hum Mol Genet. 1995 Dec;4(12):2307-11
(Latest) J:174947 Matsuda A, et al., Generation of mice deficient in RNA-binding motif protein 3 (RBM3) and characterization of its role in innate immune responses and cell growth. Biochem Biophys Res Commun. 2011 Jul 22;411(1):7-13
All references(50)
Other
accession IDs
MGI:1919317

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/21/2014
MGI 5.20
The Jackson Laboratory