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Coq4
Gene Detail
Symbol

Name
ID
Coq4
coenzyme Q4 homolog (yeast)
MGI:1098826
Synonyms
D2Ertd97e, EST-MNCb4625
Feature Type
protein coding gene
Genetic Map
Chromosome 2
20.62 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr2:29787493-29797935 bp, + strand
From VEGA annotation of GRCm38

  10443 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:68641  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: COQ4
Protein SuperFamily: ubiquinone biosynthesis protein COQ4
Gene Tree: Coq4

Human
homologs
COQ4, coenzyme Q4
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 51117
neXtProt AC: NX_Q9Y3A0

Human Synonyms: CGI-92, COQ10D7

Human Chr (Location): 9q34.11; chr9:128322512-128334072 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human COQ4

Mutations,
alleles, and
phenotypes
All mutations/alleles(13) : Gene trapped(11) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Coq4 interacts with 210 markers (Mir15b, Mir16-2, Mir19a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Process ubiquinone biosynthetic process
Component membrane, mitochondrial inner membrane, ...
Function molecular_function
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (20)    Tissues (15)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 3
Northern blot 17
cDNA source data(31)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase coq4 ; ZFIN coq4    NEW 
Molecular
reagents
All nucleic(33) cDNA(31) Primer pair(1) Other(1)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000012685 (Evidence)
Ensembl Gene Model ENSMUSG00000026798 (Evidence)
Entrez Gene 227683 (Evidence)
UniGene 245948
DFCI TC1581142, TC1593888
NIA Mouse Gene Index U001561
Consensus CDS Project CCDS15857.1
International Mouse Phenotyping Consortium Status Coq4
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000012685 VEGA Gene Model | MGI Sequence Detail 10443 C57BL/6J ±  kb
transcript OTTMUST00000030237 VEGA | MGI Sequence Detail 1991 Not Applicable 
polypeptide OTTMUSP00000013606 VEGA | MGI Sequence Detail 266 Not Applicable 

For the selected sequences
All sequences(56) RefSeq(7) UniProt(6)
Polymorphisms
SNPs within 2kb(47 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR007715 Ubiquinone biosynthesis protein Coq4
InterPro IPR027540 Ubiquinone biosynthesis protein Coq4, eukaryotes
Protein Ontology PR:000005753 ubiquinone biosynthesis protein COQ4, mitochondrial
References
(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(36)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory