Commd2 MGI Mouse Gene Detail - MGI:1098806

Symbol

Commd2
Name

COMM domain containing 2
Synonyms

1190017G07Rik, D3Ertd176e, HSPC042

Feature Type

protein coding gene
IDs

MGI:1098806
NCBI Gene: 52245
Alliance

genome feature page
Transcription Start Sites

1 TSS

Sequence Map

Chr3:57551770-57559105 bp, - strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 3, 27.94 cM
Mapping Data

3 experiments

SNPs within 2kb

349 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1098806	protein coding gene	Chr3:57551770-57559136 (-)
129S1/SvImJ	ENSMUSG00200022926	protein coding gene	Chr3:54422934-54430301 (-)
A/J	ENSMUSG00195031567	protein coding gene	Chr3:54333147-54340782 (-)
AKR/J	ENSMUSG00220029163	protein coding gene	Chr3:54392780-54400147 (-)
BALB/cJ	ENSMUSG00180022654	protein coding gene	Chr3:54419435-54426803 (-)
C3H/HeJ	ENSMUSG00175008490	protein coding gene	Chr3:54260854-54268220 (-)
C57BL/6NJ	ENSMUSG00215008261	protein coding gene	Chr3:54704916-54712283 (-)
CAROLI/EiJ	no annotation
CAST/EiJ	ENSTCUG00005002317	protein coding gene	Chr3:54030724-54038102 (-)
CBA/J	ENSMUSG00210003395	protein coding gene	Chr3:54376568-54383934 (-)
DBA/2J	ENSMUSG00185027070	protein coding gene	Chr3:54548368-54555740 (-)
FVB/NJ	ENSMUSG00205003543	protein coding gene	Chr3:53534187-53541809 (-)
JF1/MsJ	ENSUMUG00000001402	protein coding gene	Chr3:53946056-53953398 (-)
LP/J	ENSMUSG00230003913	protein coding gene	Chr3:56559694-56567061 (-)
NOD/ShiLtJ	ENSMUSG00190028811	protein coding gene	Chr3:54737642-54745008 (-)
NZO/HlLtJ	ENSMUSG00225015609	protein coding gene	Chr3:59172145-59179512 (-)
PWK/PhJ	ENSLUMG00010004962	protein coding gene	Chr3:54056028-54063375 (-)
SPRET/EiJ	ENSMSPG00010007430	protein coding gene	Chr3:54918734-54923970 (-)
WSB/EiJ	ENSIUOG00005007881	protein coding gene	Chr3:54509342-54516694 (-)

Human Ortholog

COMMD2, COMM domain containing 2

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

COMMD2, COMM domain containing 2
Synonyms

HSPC042
Links

HGNC:24993

NCBI Gene ID: 51122

UniProt: Q86X83
Chr Location

3q25.1; chr3:149734667-149752495 (-) GRCh38

MGI Vertebrate Homology

Commd2 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: COMMD2
Gene Tree

Commd2

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References

1 with disease annotations

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Phenotype Summary

10 phenotype references

All Mutations and Alleles

7
Gene trapped

1
Radiation induced

1
Targeted

5
Genomic Mutations

1 involving Commd2
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

12 strains or lines available

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All GO Annotations

5
GO References

4

Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.

Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

597
cDNA Data

67

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase commd2

ZFIN commd2

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All Sequences

48
RefSeq

2
UniProt

3
CCDS

CCDS17362.1

Ensembl

ENSMUSG00000036513 (Evidence)
NCBI Gene

52245

			Length	Strain/Species	Flank
genomic	52245	NCBI Gene Model \| MGI Sequence Detail	7336	C57BL/6J	± kb
transcript	NM_175095	RefSeq \| MGI Sequence Detail	2961	ZRU/MplStud
polypeptide	Q8BXC6	UniProt \| EBI \| MGI Sequence Detail	199	Not Applicable

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UniProt

3 Sequences
Protein Ontology

PR:000031978 COMM domain-containing protein 2

(term hierarchy)
InterPro Domains

IPR017920 COMM domain

IPR037354 COMM domain-containing protein 2
GlyGen

Q8BXC6 1 site, 1 O-linked glycan (1 site)

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All nucleic 68

cDNA 67

Primer pair 1

Microarray probesets 3

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MGI:1916178, MGI:2147842

Summaries

All 39

Diseases 1

Gene Ontology 4

Phenotypes 10
Earliest

J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
Latest

J:302829 Lu J, et al., Mouse models for human hyperuricaemia: a critical review. Nat Rev Rheumatol. 2019 Jul;15(7):413-426

TSS for Commd2:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr33336	Chr3:57559088-57559148 (-)	-13 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/15/2026 MGI 6.29