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Sgol2a
Gene Detail
Symbol

Name
ID
Sgol2a
shugoshin-like 2a (S. pombe)
MGI:1098767
Synonyms
1110007N04Rik, 5730576N04Rik, D1Ertd8e, Sgol2, Tripin
Feature Type
protein coding gene
Genetic Map
Chromosome 1
28.86 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr1:57995971-58025899 bp, + strand
From VEGA annotation of GRCm38

  29929 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:51867  Vertebrate Homology Class
1 human; 2 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog

HCOP human homology predictions: SGOL2
Gene Tree: Sgol2a

Human
homologs
SGOL2, shugoshin-like 2 (S. pombe)
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 151246
neXtProt AC: NX_Q562F6

Human Synonyms: SGO2, TRIPIN

Human Chr (Location): 2q33.1; chr2:200524802-200584095 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(44) : Gene trapped(41) Targeted(3)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Mice homozygous for a null mutation display male and female infertility with abnormalities in meiosis but not in mitosis.
 
Interactions
Sgol2a interacts with 271 markers (Mir1b, Mir7-1, Mir7-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (20 annotations)
Process cell cycle, cell division, ...
Component chromosome, chromosome, centromeric region, ...
Function protein binding
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (137)    Tissues (100)    Images (26)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 133
RT-PCR 4
cDNA source data(19)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(21) cDNA(19) Primer pair(2)
Microarray probesets(6)
Other database
links
VEGA Gene Model OTTMUSG00000021832 (Evidence)
Ensembl Gene Model ENSMUSG00000026039 (Evidence)
Entrez Gene 68549 (Evidence)
DoTS DT.101371442, DT.101376049, DT.103573462, DT.91443295, DT.93996444, DT.93996495
NIA Mouse Gene Index U000300
Consensus CDS Project CCDS35574.1
International Mouse Phenotyping Consortium Status Sgol2a
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000021832 VEGA Gene Model | MGI Sequence Detail 29929 C57BL/6J ±  kb
transcript OTTMUST00000051809 VEGA | MGI Sequence Detail 4939 Not Applicable 
polypeptide OTTMUSP00000024449 VEGA | MGI Sequence Detail 1164 Not Applicable 

For the selected sequences
All sequences(43) RefSeq(4) UniProt(1)
Polymorphisms
SNPs within 2kb(136 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR026706 Shugoshin-like 2
Protein Ontology PR:000014799 shugoshin-like 2
References
(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:216866 Kim J, et al., Meikin is a conserved regulator of meiosis-I-specific kinetochore function. Nature. 2014 Dec 24;
All references(51)
Other
accession IDs
MGI:1915799, MGI:1917915, MGI:2138427, MGI:2138513

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory