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Ctdsp2 Gene Detail
Summary
  • Symbol
    Ctdsp2
  • Name
    CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
  • Synonyms
    D10Ertd73e, OS4, SCP2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1098748
    NCBI Gene: 52468
  • Gene Overview
    MyGene.info: CTDSP2
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:126978717-126999975 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 74.35 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    120 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1098748
protein coding gene Chr10:126978717-126999975 (.)
129S1/SvImJ MGP_129S1SvImJ_G0017797
protein coding gene Chr10:130546120-130571794 (+)
A/J MGP_AJ_G0017772
protein coding gene Chr10:125335546-125340463 (+)
AKR/J MGP_AKRJ_G0017735
protein coding gene Chr10:129033263-129054993 (+)
BALB/cJ MGP_BALBcJ_G0017736
protein coding gene Chr10:125724072-125751455 (+)
C3H/HeJ MGP_C3HHeJ_G0017560
protein coding gene Chr10:129160850-129184268 (+)
C57BL/6NJ MGP_C57BL6NJ_G0018191
protein coding gene Chr10:134975094-134998441 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015871
protein coding gene Chr10:119347483-119367980 (+)
CAST/EiJ MGP_CASTEiJ_G0017120
protein coding gene Chr10:129809506-129834042 (+)
CBA/J MGP_CBAJ_G0017529
protein coding gene Chr10:140389414-140416189 (+)
DBA/2J MGP_DBA2J_G0017635
protein coding gene Chr10:124409116-124431304 (+)
FVB/NJ MGP_FVBNJ_G0017630
protein coding gene Chr10:123357208-123379368 (+)
LP/J MGP_LPJ_G0017709
protein coding gene Chr10:131113916-131142520 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0017658
protein coding gene Chr10:143127006-143155468 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0018231
protein coding gene Chr10:129087544-129110683 (+)
PWK/PhJ MGP_PWKPhJ_G0016905
protein coding gene Chr10:124597943-124620214 (+)
SPRET/EiJ MGP_SPRETEiJ_G0016697
protein coding gene Chr10:128109143-128134904 (+)
WSB/EiJ MGP_WSBEiJ_G0017181
protein coding gene Chr10:129309570-129327671 (+)



Homology
more
  • Human Ortholog
    CTDSP2, CTD small phosphatase 2
  • Vertebrate Orthologs
    8
  • Human Ortholog
    CTDSP2, CTD small phosphatase 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    OS4, PSR2, SCP2
  • Links
    NCBI Gene ID: 10106
    neXtProt AC: NX_O14595
    UniProt: O14595

  • Chr Location
    12q14.1; chr12:57819927-57846964 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 52468 NCBI Gene Model | MGI Sequence Detail 21259 C57BL/6J ±  kb
    transcript NM_001113470 RefSeq | MGI Sequence Detail 4823 C57BL/6  
    polypeptide Q8BX07 UniProt | EBI | MGI Sequence Detail 270 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 356
      cDNA 354
      Primer pair 2

      Microarray probesets 7
    Other
    Accession IDs
    less
    MGI:2143650
    References
    more
    • Summaries
      All 45
      Developmental Gene Expression 8
      Gene Ontology 6
      Phenotypes 8
    • Earliest
      J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
    • Latest
      J:261961 Zhang H, et al., Cohesive Regulation of Neural Progenitor Development by microRNA miR-26, Its Host Gene Ctdsp and Target Gene Emx2 in the Mouse Embryonic Cerebral Cortex. Front Mol Neurosci. 2018;11:44

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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    last database update
    11/06/2018
    MGI 6.13
    The Jackson Laboratory