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Tmc6
Gene Detail
 Symbol
Name
ID
Tmc6
transmembrane channel-like gene family 6
MGI:1098686
Synonyms D11Ertd204e, EVER1
Feature Type protein coding gene
Genetic Map
Chromosome 11
82.96 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr11:117765988-117782198 bp, - strand
From VEGA annotation of GRCm38

  16211 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:5258  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Tmc6

Human
homologs
Human Homolog TMC6, transmembrane channel-like 6
NCBI Gene ID 11322
neXtProt AC  NX_Q7Z403
Human Synonyms  EV1, EVER1, EVIN1, LAK-4P
Human Chr (Location)  17q25.3; chr17:78112918-78132407 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human TMC6
Alleles
and
phenotypes
All alleles(10) : Targeted(1) Gene trapped(9)
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process ion transport, transport
Component cytoplasm, endoplasmic reticulum, ...
Function molecular_function
External Resources: FuncBase
Expression
cDNA source data(82)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(84) cDNA(83) Primer pair(1)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000003673 (Evidence)
Ensembl Gene ModelENSMUSG00000025572 (Evidence)
Entrez Gene217353 (Evidence)
UniGene286963
DFCITC1574338, TC1595137, TC1596690, TC1708326
DoTSDT.101290108, DT.101362160, DT.91443779, DT.97356669
NIA Mouse Gene IndexU033668
Consensus CDS ProjectCCDS25687.1, CCDS25688.1
International Mouse Knockout Project StatusTmc6
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000003673 VEGA Gene Model | MGI Sequence Detail 16211 C57BL/6J ±  kb
transcript OTTMUST00000007941 VEGA | MGI Sequence Detail 2865 Not Applicable 
polypeptide OTTMUSP00000003855 VEGA | MGI Sequence Detail 810 Not Applicable 

For the selected sequences
All sequences(111) RefSeq(28) UniProt(8)
Polymorphisms SNPs within 2kb(67 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR012496 TMC
Protein Ontology PR:000016397 transmembrane channel-like protein 6
References (Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(33)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory