Tmc6
Gene Detail

Symbol Name ID

Tmc6 transmembrane channel-like gene family 6 MGI:1098686

Synonyms

D11Ertd204e, EVER1

Feature Type

protein coding gene

Genetic Map

Chromosome 11

82.96 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr11:117765988-117782198 bp, - strand From VEGA annotation of GRCm38   16211 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:5258  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Tmc6

Human homologs

Human Homolog		TMC6, transmembrane channel-like 6
NCBI Gene ID		11322
neXtProt AC		NX_Q7Z403
Human Synonyms		EV1, EVER1, EVIN1, LAK-4P
Human Chr (Location)		17q25.3; chr17:76108999-76128488 (-)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human TMC6

Alleles and phenotypes

All alleles(10) : Targeted(1) Gene trapped(9)

Gene Ontology (GO) classifications

All GO classifications: (6 annotations)

Process	biological_process
Component	endoplasmic reticulum, integral to membrane, ...
Function	molecular_function

External Resources: FuncBase

Expression

cDNA source data(82)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(84) cDNA(83) Primer pair(1)
Microarray probesets(2)

Other database links

VEGA Gene Model	OTTMUSG00000003673 (Evidence)
Ensembl Gene Model	ENSMUSG00000025572 (Evidence)
Entrez Gene	217353 (Evidence)
UniGene	286963
DFCI	TC1574338, TC1595137, TC1596690, TC1708326
DoTS	DT.101290108, DT.101362160, DT.91443779, DT.97356669
NIA Mouse Gene Index	U033668
Consensus CDS Project	CCDS25687.1, CCDS25688.1
International Mouse Knockout Project Status	Tmc6

Sequences

Length	Strain/Species
genomic	OTTMUSG00000003673	VEGA Gene Model | MGI Sequence Detail	16211	C57BL/6J
transcript	OTTMUST00000007941	VEGA | MGI Sequence Detail	2865	Not Applicable
polypeptide	OTTMUSP00000003855	VEGA | MGI Sequence Detail	810	Not Applicable

All sequences(87) RefSeq(4) UniProt(8)

Polymorphisms

SNPs(42 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR012496	TMC
Protein Ontology	PR:000016397	transmembrane channel-like protein 6

References

(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(32)