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Anapc4 Gene Detail
Summary
  • Symbol
    Anapc4
  • Name
    anaphase promoting complex subunit 4
  • Synonyms
    2610306D21Rik, APC4, D5Ertd249e
  • Feature Type
    protein coding gene
  • IDs
    MGI:1098673
    NCBI Gene: 52206
  • Gene Overview
    MyGene.info: ANAPC4
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr5:52834012-52867797 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      33786 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 28.81 cM, cytoband C1
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    ANAPC4, anaphase promoting complex subunit 4
  • Vertebrate Orthologs
    10
  • Human Ortholog
    ANAPC4, anaphase promoting complex subunit 4
    Orthology source: HomoloGene, HGNC
  • Synonyms
    APC4
  • Links
    NCBI Gene ID: 29945
    neXtProt AC: NX_Q9UJX5
    UniProt: Q9UJX5

  • Chr Location
    4p15.2; chr4:25377226-25418498 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    25 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic OTTMUSG00000023353 VEGA Gene Model | MGI Sequence Detail 33786 C57BL/6J ±  kb
    transcript OTTMUST00000056627 VEGA | MGI Sequence Detail 3854 Not Applicable  
    polypeptide OTTMUSP00000027238 VEGA | MGI Sequence Detail 807 Not Applicable  
    For the selected sequence
    Polymorphisms
    less
    • SNPs within 2kb
      121 from dbSNP Build 142
    Protein
    Information
    less
    • UniProt
      7 Sequences
    • Protein Ontology
      PR:000004017 anaphase-promoting complex subunit 4
    • InterPro Domains
      IPR024789 Anaphase-promoting complex subunit 4
      IPR024790 Anaphase-promoting complex subunit 4 long domain
      IPR017169 Anaphase-promoting complex subunit 4, metazoa
      IPR024977 Anaphase-promoting complex subunit 4, WD40 domain
      IPR036322 WD40-repeat-containing domain superfamily
      IPR015943 WD40/YVTN repeat-like-containing domain superfamily
    Molecular
    Reagents
    less
    • All nucleic 124
      cDNA 123
      Primer pair 1

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:1915174
    References
    more
    • Summaries
      All 58
      Developmental Gene Expression 3
      Gene Ontology 5
      Phenotypes 25
    • Earliest
      J:5021 Batchelor AL, et al., A comparison of the mutagenic effectiveness of chronic neutron- and gamma-irradiation of mouse spermatogonia. Mutat Res. 1966 Jun;3(3):218-29
    • Latest
      J:236599 Dickinson ME, et al., High-throughput discovery of novel developmental phenotypes. Nature. 2016 Sep 14;537(7621):508-514

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
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    last database update
    10/16/2018
    MGI 6.12
    The Jackson Laboratory