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Rif1
Gene Detail
 Symbol
Name
ID
Rif1
Rap1 interacting factor 1 homolog (yeast)
MGI:1098622
Synonyms 5730435J01Rik, 6530403D07Rik, D2Ertd145e
Feature Type protein coding gene
Genetic Map
Chromosome 2
29.98 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr2:52072842-52122383 bp, + strand
From VEGA annotation of GRCm38

  49542 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:41231  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Rif1

Human
homologs
Human Homolog RIF1, RAP1 interacting factor homolog (yeast)
NCBI Gene ID 55183
neXtProt AC  NX_Q5UIP0
Human Chr (Location)  2q23.3; chr2:151409883-151477346 (+)  GRCh38
Alleles
and
phenotypes
All alleles(75) : Targeted(5) Gene trapped(70)
 
Mice homozygous for a knock-out allele exhibit embryonic lethality. Mice homozygous for a gene trap allele exhibit embryonic and postnatal lethality, reduced fertility, and decreased cell proliferation.
 
Gene Ontology
(GO)
classifications
All GO classifications: (18 annotations)
Process cell cycle, cellular response to DNA damage stimulus, ...
Component chromosome, chromosome, telomeric region, ...
Function protein binding
External Resources: FuncBase
Expression
Literature Summary: (6 records)
Data Summary: Results (158)    Tissues (77)    Images (45)
Theiler Stages: 1, 2, 3, 4, 5, 6, 8, 9, 11, 13, 15, 19, 20, 21, 23, 25, 28
Assay TypeResults
Immunohistochemistry 52
RNA in situ 33
Northern blot 12
Western blot 10
RT-PCR 51
cDNA source data(21)
External Resources: Allen Institute   GENSAT   GEO   ArrayExpress
Molecular
reagents
All nucleic(24) cDNA(21) Primer pair(3)
Microarray probesets(8)
Other database
links
VEGA Gene ModelOTTMUSG00000012437 (Evidence)
Ensembl Gene ModelENSMUSG00000036202 (Evidence)
Entrez Gene51869 (Evidence)
DFCITC1574995, TC1606318, TC1620605, TC1621632
DoTSDT.101362328, DT.101722111, DT.101735397, DT.110703950, DT.110703956, DT.40181032, DT.532722, DT.87053699, DT.97392446
NIA Mouse Gene IndexU001752, U042291
Consensus CDS ProjectCCDS50583.1
International Mouse Knockout Project StatusRif1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000012437 VEGA Gene Model | MGI Sequence Detail 49542 C57BL/6J ±  kb
transcript OTTMUST00000029579 VEGA | MGI Sequence Detail 8497 Not Applicable 
polypeptide OTTMUSP00000013312 VEGA | MGI Sequence Detail 2426 Not Applicable 

For the selected sequences
All sequences(78) RefSeq(14) UniProt(3)
Polymorphisms SNPs within 2kb(282 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR016024 Armadillo-type fold
InterPro IPR022031 Rap1-interacting factor 1 N-terminal
Protein Ontology PR:000014000 telomere-associated protein RIF1
References (Earliest) J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-le-grand). 1999 Jul;45(5):737-50
(Latest) J:201508 Daxinger L, et al., An ENU mutagenesis screen identifies novel and known genes involved in epigenetic processes in the mouse. Genome Biol. 2013 Sep 11;14(9):R96
All references(58)
Other
accession IDs
MGI:1922959, MGI:1923494, MGI:2139159, MGI:2139383

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory