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Psmc3ip
Gene Detail
 Symbol
Name
ID
Psmc3ip
proteasome (prosome, macropain) 26S subunit, ATPase 3, interacting protein
MGI:1098610
Synonyms HOP2, Tbpip
Feature Type protein coding gene
Genetic Map
Chromosome 11
64.19 cM, cytoband D
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr11:101091823-101095436 bp, - strand
From VEGA annotation of GRCm38

  3614 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:5940  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 zebrafish

Gene Tree: Psmc3ip

Human
homologs
Human Homolog PSMC3IP, PSMC3 interacting protein
NCBI Gene ID 29893
neXtProt AC  NX_Q9P2W1
Human Synonyms  GT198, HOP2, HUMGT198A, ODG3, TBPIP
Human Chr (Location)  17q21.2; chr17:42572310-42577831 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human PSMC3IP
Alleles
and
phenotypes
All alleles(11) : Targeted(3) Gene trapped(8)
 
Homozygotes for targeted null mutations are mice were viable, showed no overt anatomical defects in somatic tissues, but are infertile in both sex due to absence of gametes.
 
Gene Ontology
(GO)
classifications
All GO classifications: (15 annotations)
Process DNA recombination, meiotic nuclear division, ...
Component nucleus, proteasome complex
Function androgen receptor binding, DBD domain binding, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (107)    Tissues (8)    Images (46)
Theiler Stages: 23
Assay TypeResults
RNA in situ 107
cDNA source data(7)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(7) cDNA(7)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000002691 (Evidence)
Ensembl Gene ModelENSMUSG00000019303 (Evidence)
Entrez Gene19183 (Evidence)
NIA Mouse Gene IndexU033442
Consensus CDS ProjectCCDS25448.1
International Mouse Knockout Project StatusPsmc3ip
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000002691 VEGA Gene Model | MGI Sequence Detail 3614 C57BL/6J ±  kb
transcript OTTMUST00000005301 VEGA | MGI Sequence Detail 1291 Not Applicable 
polypeptide OTTMUSP00000002517 VEGA | MGI Sequence Detail 217 Not Applicable 

For the selected sequences
All sequences(37) RefSeq(8) UniProt(4)
Polymorphisms SNPs within 2kb(18 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR010776 Tat binding protein 1-interacting
InterPro IPR011991 Winged helix-turn-helix DNA-binding domain
Protein Ontology PR:000013381 homologous-pairing protein 2
References (Earliest) J:43564 Tanaka T, et al., Molecular cloning and characterization of a novel TBP-1 interacting protein (TBPIP):enhancement of TBP-1 action on Tat by TBPIP. Biochem Biophys Res Commun. 1997 Oct 9;239(1):176-81
(Latest) J:202231 Smagulova F, et al., Suppression of genetic recombination in the pseudoautosomal region and at subtelomeres in mice with a hypomorphic Spo11 allele. BMC Genomics. 2013;14:493
All references(40)
Other
accession IDs
MGI:2144650

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory