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Alg3 Gene Detail
Summary
  • Symbol
    Alg3
  • Name
    asparagine-linked glycosylation 3 (alpha-1,3-mannosyltransferase)
  • Synonyms
    D16Ertd36e
  • Feature Type
    protein coding gene
  • IDs
    MGI:1098592
    NCBI Gene: 208624
  • Gene Overview
    MyGene.info: ALG3
Location & Maps
more
  • Sequence Map
    Chr16:20605451-20610768 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      5318 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 16, 12.48 cM
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    ALG3, ALG3, alpha-1,3- mannosyltransferase
  • Vertebrate Orthologs
    10
  • Human Ortholog
    ALG3, ALG3, alpha-1,3- mannosyltransferase
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CDG1D, CDGS4, CDGS6, D16Ertd36e, not, Not56, NOT56L
  • Links
    NCBI Gene ID: 10195
    neXtProt AC: NX_Q92685

  • Chr Location
    3q27.1; chr3:184242329-184249525 (-)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human ALG3 associations

Human Disease Mouse Models
       Congenital Disorder of Glycosylation, Type ID; CDG1D   OMIM: 601110
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotype references
  • All Mutations and Alleles
    6
  • Gene trapped
    4
  • Targeted
    2
  • Incidental Mutations
    APF
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000025946 VEGA Gene Model | MGI Sequence Detail 5318 C57BL/6J ±  kb
transcript OTTMUST00000063986 VEGA | MGI Sequence Detail 1451 Not Applicable  
polypeptide OTTMUSP00000031732 VEGA | MGI Sequence Detail 438 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    46 from dbSNP Build 142
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000003944 dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase
  • EC
  • InterPro Domains
    IPR007873 Glycosyltransferase, ALG3
Molecular
Reagents
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  • All nucleic 43
    cDNA 42
    Primer pair 1

    Microarray probesets 3
References
more
  • Summaries
    All 31
    Developmental Gene Expression 3
    Gene Ontology 4
    Phenotypes 4
  • Earliest
    J:50320 Pappano WN, et al., Coding sequence and expression patterns of mouse chordin and mapping of the cognate mouse chrd and human CHRD genes. Genomics. 1998 Sep 1;52(2):236-9
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/27/2016
MGI 6.05
The Jackson Laboratory