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Alg3
Gene Detail
Symbol

Name
ID
Alg3
asparagine-linked glycosylation 3 (alpha-1,3-mannosyltransferase)
MGI:1098592
Synonyms
D16Ertd36e
Feature Type
protein coding gene
Genetic Map
Chromosome 16
12.48 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr16:20605451-20610768 bp, - strand
From VEGA annotation of GRCm38

  5318 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:4228  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase
Gene Tree: Alg3

Human
homologs
Human Homolog ALG3, ALG3, alpha-1,3- mannosyltransferase
NCBI Gene ID 10195
neXtProt AC  NX_Q92685
Human Synonyms  CDG1D, CDGS4, D16Ertd36e, Not56, NOT56L
Human Chr (Location)  3q27.1; chr3:184242329-184249525 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human ALG3
Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Gene trapped(4) Targeted(2)
Incidental mutations (data from APF )
Interactions
Alg3 interacts with 201 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (3 records)
Data Summary: Results (108)    Tissues (103)    Images (5)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 108
cDNA source data(41)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(43) cDNA(42) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000025946 (Evidence)
Ensembl Gene ModelENSMUSG00000033809 (Evidence)
Entrez Gene208624 (Evidence)
UniGene24950
DFCITC1601559, TC1581077
DoTSDT.94194573, DT.530708
NIA Mouse Gene IndexU036890
EC2.4.1.258
Consensus CDS ProjectCCDS37289.1
International Mouse Knockout Project StatusAlg3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000025946 VEGA Gene Model | MGI Sequence Detail 5318 C57BL/6J ±  kb
transcript OTTMUST00000063986 VEGA | MGI Sequence Detail 1451 Not Applicable 
polypeptide OTTMUSP00000031732 VEGA | MGI Sequence Detail 438 Not Applicable 

For the selected sequences
All sequences(46) RefSeq(8) UniProt(5)
Polymorphisms
SNPs within 2kb(46 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR007873 Glycosyltransferase, ALG3
Protein Ontology PR:000003944 dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase
References
(Earliest) J:50320 Pappano WN, et al., Coding sequence and expression patterns of mouse chordin and mapping of the cognate mouse chrd and human CHRD genes. Genomics. 1998 Sep 1;52(2):236-9
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(36)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory