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Npy6r Gene Detail
Summary
  • Symbol
    Npy6r
  • Name
    neuropeptide Y receptor Y6
  • Feature Type
    protein coding gene
  • IDs
    MGI:1098590
    NCBI Gene: 18169
Location & Maps
more
  • Sequence Map
    Chr18:44270127-44277700 bp, + strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      7574 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 18, 23.74 cM
  • Mapping Data
    2 experiments
Homology
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Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    41 phenotypes from 2 alleles in 2 genetic backgrounds
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a reporter allele exhibit enhanced performance on the rotarod test.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 18169 NCBI Gene Model | MGI Sequence Detail 7574 C57BL/6J ±  kb
transcript NM_010935 RefSeq | MGI Sequence Detail 2567 C57BL/6  
polypeptide Q61212 UniProt | EBI | MGI Sequence Detail 371 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    41 from dbSNP Build 142
Protein
Information
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  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000001624 neuropeptide Y receptor 6
  • InterPro Domains
    IPR017452 GPCR, rhodopsin-like, 7TM
    IPR000276 G protein-coupled receptor, rhodopsin-like
    IPR000986 Neuropeptide Y6 receptor
    IPR000611 Neuropeptide Y receptor family
Molecular
Reagents
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  • All nucleic 12
    Genomic 3
    cDNA 7
    Primer pair 1
    Other 1

    Microarray probesets 4
References
more
  • Summaries
    All 30
    Developmental Gene Expression 3
    Gene Ontology 4
    Phenotypes 5
  • Earliest
    J:34096 Weinberg DH, et al., Cloning and expression of a novel neuropeptide Y receptor. J Biol Chem. 1996 Jul 12;271(28):16435-8
  • Latest
    J:230880 Khor EC, et al., The y6 receptor suppresses bone resorption and stimulates bone formation in mice via a suprachiasmatic nucleus relay. Bone. 2016 Mar;84:139-47

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/27/2016
MGI 6.05
The Jackson Laboratory