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Rab11fip5 Gene Detail
Summary
  • Symbol
    Rab11fip5
  • Name
    RAB11 family interacting protein 5 (class I)
  • Synonyms
    9130206P09Rik, D6Ertd32e, GAF1, mKIAA0857, RIP11
  • Feature Type
    protein coding gene
  • IDs
    MGI:1098586
    NCBI Gene: 52055
  • Gene Overview
    MyGene.info: RAB11FIP5
Location & Maps
more
  • Sequence Map
    Chr6:85334962-85374634 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      39673 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 37.35 cM
  • Mapping Data
    4 experiments
Homology
more
  • Human Ortholog
    RAB11FIP5, RAB11 family interacting protein 5
  • Vertebrate Orthologs
    7
  • Human Ortholog
    RAB11FIP5, RAB11 family interacting protein 5
    Orthology source: HGNC, HomoloGene
  • Synonyms
    GAF1, pp75, RIP11
  • Links
    NCBI Gene ID: 26056
    neXtProt AC: NX_Q9BXF6

  • Chr Location
    2p13; chr2:73073382-73113018 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    7 phenotype references
  • All Mutations and Alleles
    6
  • Spontaneous
    1
  • Targeted
    5
  • Genomic Mutations
    1 involving Rab11fip5
  • Incidental Mutations
Mice homozygous for a floxed allele are viable and fertile.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000057879 VEGA Gene Model | MGI Sequence Detail 39673 C57BL/6J ±  kb
transcript OTTMUST00000142119 VEGA | MGI Sequence Detail 6119 Not Applicable  
polypeptide OTTMUSP00000074189 VEGA | MGI Sequence Detail 1318 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    107 from dbSNP Build 142
Protein
Information
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  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000013584 rab11 family-interacting protein 5
  • InterPro Domains
    IPR000008 C2 domain
    IPR019018 Rab-binding domain FIP-RBD
Molecular
Reagents
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  • All nucleic 10
    cDNA 9
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
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MGI:1924936, MGI:2141742
References
more
  • Summaries
    All 36
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 7
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:221637 Bacaj T, et al., Synaptic Function of Rab11Fip5: Selective Requirement for Hippocampal Long-Term Depression. J Neurosci. 2015 May 13;35(19):7460-74

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/15/2016
MGI 6.04
The Jackson Laboratory