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Camk1
Gene Detail
 Symbol
Name
ID
Camk1
calcium/calmodulin-dependent protein kinase I
MGI:1098535
Synonyms CaMKIalpha, D6Ertd263e
Feature Type protein coding gene
Genetic Map
Chromosome 6
52.75 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr6:113334124-113343984 bp, - strand
From VEGA annotation of GRCm38

  9861 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:117458  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: kinase-related transforming protein
Gene Tree: Camk1

Human
homologs
Human Homolog CAMK1, calcium/calmodulin-dependent protein kinase I
NCBI Gene ID 8536
neXtProt AC  NX_Q14012
Human Synonyms  CAMKI
Human Chr (Location)  3p25.3; chr3:9757345-9769992 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(11) : Gene trapped(5) Targeted(6)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Camk1 interacts with 36 markers (Mir22, Mir96, Mir141, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (39 annotations)
Process cell cycle, cell differentiation, ...
Component calcium- and calmodulin-dependent protein kinase complex, cell, ...
Function ATP binding, calmodulin binding, ...
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (54)    Tissues (31)    Images (21)
Theiler Stages: 19, 23, 26, 28
Assay TypeResults
RNA in situ 53
Western blot 1
cDNA source data(10)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(13) cDNA(11) Primer pair(2)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000022452 (Evidence)
Ensembl Gene ModelENSMUSG00000030272 (Evidence)
Entrez Gene52163 (Evidence)
DFCITC1577473
DoTSDT.491757, DT.97339021
NIA Mouse Gene IndexU027728
EC2.7.11.17
Consensus CDS ProjectCCDS20415.1
International Mouse Knockout Project StatusCamk1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022452 VEGA Gene Model | MGI Sequence Detail 9861 C57BL/6J ±  kb
transcript OTTMUST00000053683 VEGA | MGI Sequence Detail 1496 Not Applicable 
polypeptide OTTMUSP00000025539 VEGA | MGI Sequence Detail 374 Not Applicable 

For the selected sequences
All sequences(40) RefSeq(2) UniProt(5)
Polymorphisms SNPs within 2kb(95 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR020636 Calcium/calmodulin-dependent/calcium-dependent protein kinase
InterPro IPR017441 Protein kinase, ATP binding site
InterPro IPR000719 Protein kinase, catalytic domain
InterPro IPR011009 Protein kinase-like domain
InterPro IPR002290 Serine/threonine- / dual specificity protein kinase, catalytic domain
InterPro IPR008271 Serine/threonine-protein kinase, active site
Protein Ontology PR:000004988 calcium/calmodulin-dependent protein kinase type 1
References (Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:194833 Guo L, et al., CaMKIalpha Regulates AMP Kinase-Dependent, TORC-1-Independent Autophagy during Lipopolysaccharide-Induced Acute Lung Neutrophilic Inflammation. J Immunol. 2013 Apr 1;190(7):3620-8
All references(47)
Other
accession IDs
MGI:2141437

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory