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Cpt1b
Gene Detail
Symbol

Name
ID
Cpt1b
carnitine palmitoyltransferase 1b, muscle
MGI:1098297
Synonyms
Cpt1, M-CPTI, M-CPT I
Feature Type
protein coding gene
Genetic Map
Chromosome 15
44.89 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr15:89416405-89425863 bp, - strand
From VEGA annotation of GRCm38

  9459 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:22548  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog

HCOP human homology predictions: CPT1B
Gene Tree: Cpt1b

Human
homologs
CPT1B, carnitine palmitoyltransferase 1B (muscle)
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 1375
neXtProt AC: NX_Q92523

Human Synonyms: CPT1M, CPT1-M, CPTI, CPTI-M, MCCPT1, MCPT1, M-CPT1

Human Chr (Location): 22q13.33; chr22:50568861-50578667 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Radiation induced(1) Targeted(2)
Genomic Mutations involving Cpt1b (1)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous null mice die in utero prior to E9.5. Heterozygous mutant mice exhibit susceptibility to fatal hypothermia following cold exposure, with females more severely affected.
 
Phenotype Images(2)
Interactions
Cpt1b interacts with 73 markers (Mir7-1, Mir92-2, Mir105, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (9 records)
Data Summary: Results (110)    Tissues (105)    Images (3)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 94
Northern blot 9
RT-PCR 7
cDNA source data(31)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase cpt1b ; ZFIN cpt1b    NEW 
Molecular
reagents
All nucleic(37) Genomic(3) cDNA(32) Primer pair(2)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000035434 (Evidence)
Ensembl Gene Model ENSMUSG00000078937 (Evidence)
Entrez Gene 12895 (Evidence)
UniGene 227738
DFCI TC1581482
EC 2.3.1.21
Consensus CDS Project CCDS27749.1
International Mouse Phenotyping Consortium Status Cpt1b
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000035434 VEGA Gene Model | MGI Sequence Detail 9459 C57BL/6J ±  kb
transcript OTTMUST00000090606 VEGA | MGI Sequence Detail 2895 Not Applicable 
polypeptide OTTMUSP00000049742 VEGA | MGI Sequence Detail 772 Not Applicable 

For the selected sequences
All sequences(34) RefSeq(2) UniProt(4)
Polymorphisms
RFLP(1) : SNPs within 2kb(15 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000542 Acyltransferase ChoActase/COT/CPT
Protein Ontology PR:000005836 carnitine O-palmitoyltransferase 1, muscle isoform
References
(Earliest) J:16140 Gelb BD, Genomic structure of and a cardiac promoter for the mouse carnitine palmitoyltransferase II gene. Genomics. 1993 Dec;18(3):651-5
(Latest) J:201804 Breckenridge RA, et al., Hypoxic regulation of hand1 controls the fetal-neonatal switch in cardiac metabolism. PLoS Biol. 2013 Sep;11(9):e1001666
All references(47)
Other
accession IDs
MGD-MRK-2118

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory