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Cpt1b Gene Detail
Summary
  • Symbol
    Cpt1b
  • Name
    carnitine palmitoyltransferase 1b, muscle
  • Synonyms
    Cpt1, M-CPTI, M-CPT I
  • Feature Type
    protein coding gene
  • IDs
    MGI:1098297
    NCBI Gene: 12895
  • Alliance
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:89416405-89425862 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 44.89 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    14 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1098297
protein coding gene Chr15:89416405-89425863 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022235
protein coding gene Chr15:90611079-90621568 (-)
A/J MGP_AJ_G0022194
protein coding gene Chr15:87146135-87156374 (-)
AKR/J MGP_AKRJ_G0022169
protein coding gene Chr15:89728827-89738217 (-)
BALB/cJ MGP_BALBcJ_G0022200
protein coding gene Chr15:87250681-87261377 (-)
C3H/HeJ MGP_C3HHeJ_G0021970
protein coding gene Chr15:89722345-89736968 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022645
protein coding gene Chr15:93906305-93922305 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020170
protein coding gene Chr15:83371388-83380631 (-)
CAST/EiJ MGP_CASTEiJ_G0021492
protein coding gene Chr15:90502659-90516354 (-)
CBA/J MGP_CBAJ_G0021937
protein coding gene Chr15:97089628-97102185 (-)
DBA/2J MGP_DBA2J_G0022064
protein coding gene Chr15:86597135-86607162 (-)
FVB/NJ MGP_FVBNJ_G0022043
protein coding gene Chr15:85664773-85674282 (-)
LP/J MGP_LPJ_G0022135
protein coding gene Chr15:90769158-90779237 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022063
protein coding gene Chr15:101486912-101499823 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022660
protein coding gene Chr15:89763549-89775020 (-)
PWK/PhJ MGP_PWKPhJ_G0021233
protein coding gene Chr15:86660190-86670428 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021067
protein coding gene Chr15:89510580-89524006 (-)
WSB/EiJ MGP_WSBEiJ_G0021541
protein coding gene Chr15:90251866-90265197 (-)



Homology
more
  • Human Ortholog
    CPT1B, carnitine palmitoyltransferase 1B
  • Vertebrate Orthologs
    8
  • Human Ortholog
    CPT1B, carnitine palmitoyltransferase 1B
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CPT1M, CPT1-M, CPTI, CPTI-M, MCCPT1, MCPT1, M-CPT1
  • Links
    NCBI Gene ID: 1375
    neXtProt AC: NX_Q92523
    UniProt: Q92523

  • Chr Location
    22q13.33; chr22:50568861-50578667 (-)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    24 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Homozygous null mice die in utero prior to E9.5. Heterozygous mutant mice exhibit susceptibility to fatal hypothermia following cold exposure, with females more severely affected.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 12895 NCBI Gene Model | MGI Sequence Detail 9458 C57BL/6J ±  kb
transcript NM_009948 RefSeq | MGI Sequence Detail 2894 C57BL/6  
polypeptide Q924X2 UniProt | EBI | MGI Sequence Detail 772 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 38
    Genomic 3
    cDNA 33
    Primer pair 2

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-2118
References
more
  • Summaries
    All 72
    Developmental Gene Expression 13
    Diseases 1
    Gene Ontology 8
    Phenotypes 24
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:258670 Mahany EB, et al., Obesity and High-Fat Diet Induce Distinct Changes in Placental Gene Expression and Pregnancy Outcome. Endocrinology. 2018 Apr 1;159(4):1718-1733

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory