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Per1
Gene Detail
 Symbol
Name
ID
Per1
period circadian clock 1
MGI:1098283
Synonyms mPer1, m-rigui
Feature Type protein coding gene
Genetic Map
Chromosome 11
42.37 cM, cytoband B
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr11:69095217-69109960 bp, + strand
From VEGA annotation of GRCm38

  14744 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:1966  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog

Gene Tree: Per1

Human
homologs
Human Homolog PER1, period circadian clock 1
NCBI Gene ID 5187
neXtProt AC  NX_O15534
Human Synonyms  hPER, PER, RIGUI
Human Chr (Location)  17p13.1; chr17:8140470-8156405 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(16) : Gene trapped(12) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous null mice display a persistent circadian rhythm, but they have a shorter period and their ability to maintain the precision and the stability of the period is impaired.
 
Interactions
Per1 interacts with 204 markers (Mir1a-1, Mir1a-2, Mir15a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (50 annotations)
Process circadian regulation of gene expression, circadian regulation of translation, ...
Component cytoplasm, nucleus
Function chromatin DNA binding, E-box binding, ...
External Resources: FuncBase
Expression
Literature Summary: (16 records)
Data Summary: Results (121)    Tissues (118)    Images (26)
Theiler Stages: 13, 17, 19, 20, 21, 22, 23, 24, 25, 27, 28
Assay TypeResults
Immunohistochemistry 4
RNA in situ 112
RT-PCR 5
cDNA source data(62)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(69) Genomic(1) cDNA(65) Primer pair(3)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000005970 (Evidence)
Ensembl Gene ModelENSMUSG00000020893 (Evidence)
Entrez Gene18626 (Evidence)
UniGene7373
DFCITC1578230, TC1588671
DoTSDT.101409795, DT.110529609, DT.529588, DT.94198914, DT.94297792
NIA Mouse Gene IndexU012810
PDB4DJ2
Consensus CDS ProjectCCDS24882.1
International Mouse Knockout Project StatusPer1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005970 VEGA Gene Model | MGI Sequence Detail 14744 C57BL/6J ±  kb
transcript OTTMUST00000013334 VEGA | MGI Sequence Detail 4671 Not Applicable 
polypeptide OTTMUSP00000006173 VEGA | MGI Sequence Detail 1291 Not Applicable 

For the selected sequences
All sequences(62) RefSeq(10) UniProt(9)
Polymorphisms SNPs within 2kb(118 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001610 PAC motif
InterPro IPR000014 PAS domain
InterPro IPR022728 Period circadian-like, C-terminal
Protein Ontology PR:000012547 period circadian protein homolog 1
References (Earliest) J:20243 Ishida N, et al., Mouse hexamer repeat sequences homologous to the Drosophila 'period' gene. Nucleic Acids Res. 1988 Apr 25;16(8):3581
(Latest) J:210648 Adamovich Y, et al., Circadian clocks and feeding time regulate the oscillations and levels of hepatic triglycerides. Cell Metab. 2014 Feb 4;19(2):319-30
All references(159)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory