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C9
Gene Detail
Symbol

Name
ID
C9
complement component 9
MGI:1098282
Feature Type
protein coding gene
Genetic Map
Chromosome 15
2.79 cM, cytoband A1
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr15:6445327-6498751 bp, + strand
From VEGA annotation of GRCm38

  53425 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:74406  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog

Gene Tree: C9

Human
homologs
Human Homolog C9, complement component 9
NCBI Gene ID 735
neXtProt AC  NX_P02748
Human Synonyms  ARMD15, C9D
Human Chr (Location)  5p14-p12; chr5:39284275-39364553 (-)  GRCh38
Disease Associations  (2) Diseases Associated with Human C9
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
C9 interacts with 95 markers (Mir17, Mir18, Mir18b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (16 annotations)
Process blood coagulation, complement activation, alternative pathway, ...
Component blood microparticle, cytoplasm, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (27)    Tissues (2)    Images (21)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 27
cDNA source data(24)
External Resources: GEO   Expression Atlas
Molecular
reagents
All nucleic(24) cDNA(24)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000026361 (Evidence)
Ensembl Gene ModelENSMUSG00000022149 (Evidence)
Entrez Gene12279 (Evidence)
UniGene29095
DFCITC1584838
DoTSDT.530651
NIA Mouse Gene IndexU016031
Consensus CDS ProjectCCDS27367.1
International Mouse Knockout Project StatusC9
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026361 VEGA Gene Model | MGI Sequence Detail 53425 C57BL/6J ±  kb
transcript OTTMUST00000065195 VEGA | MGI Sequence Detail 2048 Not Applicable 
polypeptide OTTMUSP00000032453 VEGA | MGI Sequence Detail 561 Not Applicable 

For the selected sequences
All sequences(29) RefSeq(2) UniProt(5)
Polymorphisms
SNPs within 2kb(150 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR009030 Insulin-like growth factor binding protein, N-terminal
InterPro IPR023415 Low-density lipoprotein (LDL) receptor class A, conserved site
InterPro IPR002172 Low-density lipoprotein (LDL) receptor class A repeat
InterPro IPR001862 Membrane attack complex component/perforin/complement C9
InterPro IPR020863 Membrane attack complex component/perforin domain, conserved site
InterPro IPR020864 Membrane attack complex component/perforin (MACPF) domain
InterPro IPR000884 Thrombospondin, type 1 repeat
Protein Ontology PR:000004911 complement component C9
References
(Earliest) J:43388 Stanley KK, et al., Topological mapping of complement component C9 by recombinant DNA techniques suggests a novel mechanism for its insertion into target membranes. EMBO J. 1987 Jul;6(7):1951-7
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(26)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/11/2014
MGI 5.20
The Jackson Laboratory