Gse1 Gene Detail

Summary

• Symbol
  Gse1
• Name
  genetic suppressor element 1, coiled-coil protein
• Synonyms
  mKIAA0182

• Feature Type
  protein coding gene
• IDs
  MGI:1098275
  NCBI Gene: 382034
• Gene Overview
  MyGene.info: GSE1

Location & Maps

• Sequence Map
  Chr8:120228456-120581390 bp, + strand
• From VEGA annotation of GRCm38
  

  Mouse Genome Browser
  
  

• Download
  Sequence
    352935 bp   ±  kb flank
  
  
• Genome Browsers
  VEGA | Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 8, 69.69 cM
• Mapping Data
  1 experiment

Homology

• Human Ortholog
  GSE1, Gse1 coiled-coil protein

• Vertebrate Orthologs
  10

• Human Ortholog
  GSE1, Gse1 coiled-coil protein
  Orthology source: HomoloGene, HGNC
• Synonyms
  CRHSP24, KIAA0182
• Links
  HGNC:28979

  NCBI Gene ID: 23199

  neXtProt AC: NX_Q14687

  
  
• Chr Location
  16q24.1; chr16:85170003-85676206 (+)  GRCh38.p2

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• HomoloGene
  Vertebrate Homology Class 40964
  1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed
  
• HCOP
  human homology predictions: GSE1
• Gene Tree
  Gse1
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  8 phenotypes from 1 allele in 1 genetic background
  3 phenotype references
  

• All Mutations and Alleles
  2
• Targeted
  2
• Incidental Mutations
  Mutagenetix , APF , CvDC

Gene Ontology
(GO)
Classifications

• External Resources
  FuncBase

Expression

• cDNA Data
  10
• Literature Summary
  1

• Other Mouse Links
  Allen Institute
  GEO

Interactions

• Gse1 interacts with 337 markers (Mir1a-1, Mir1a-2, Mir1b, ...) View All

Sequences &
Gene Models

• All Sequences
  56
• RefSeq
  16
• UniProt
  2
• CCDS
  CCDS52687.1, CCDS52688.1, CCDS52689.1

• VEGA
  OTTMUSG00000031594 (Evidence)
• Ensembl
  ENSMUSG00000031822 (Evidence)
• NCBI Gene
  382034

Representative Sequences			Length	Strain/Species
genomic	OTTMUSG00000031594	VEGA Gene Model | MGI Sequence Detail	352935	C57BL/6J
transcript	OTTMUST00000078247	VEGA | MGI Sequence Detail	7127	Not Applicable
polypeptide	OTTMUSP00000041595	VEGA | MGI Sequence Detail	1223	Not Applicable

Polymorphisms

• SNPs within 2kb
  800 from dbSNP Build 142

Protein
Information

• UniProt
  2 Sequences
• Protein Ontology
  PR:000008283 genetic suppressor element 1
• InterPro Domains
  IPR022207 Genetic suppressor element-like

Molecular
Reagents

• All nucleic 10

  cDNA 10

  
  

  Microarray probesets 5

References

• Summaries
  All 23

  Developmental Gene Expression 1

  Phenotypes 3
• Earliest
  J:43245 Gudkov AV, et al., Cloning mammalian genes by expression selection of genetic suppressor elements: association of kinesin with drug resistance and cell immortalization. Proc Natl Acad Sci U S A. 1994 Apr 26;91(9):3744-8
• Latest
  J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42