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Kif13b Gene Detail
Summary
  • Symbol
    Kif13b
  • Name
    kinesin family member 13B
  • Synonyms
    5330429L19Rik, C130021D12Rik, GAKIN, N-3 kinesin
  • Feature Type
    protein coding gene
  • IDs
    MGI:1098265
    NCBI Gene: 16554
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:64652490-64809618 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 33.77 cM, cytoband C3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    749 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1098265
protein coding gene Chr14:64647265-64809618 (.)
129S1/SvImJ MGP_129S1SvImJ_G0021473
protein coding gene Chr14:59223245-59388296 (+)
A/J MGP_AJ_G0021432
protein coding gene Chr14:57865198-58026124 (+)
AKR/J MGP_AKRJ_G0021408
protein coding gene Chr14:59893090-60053294 (+)
BALB/cJ MGP_BALBcJ_G0021438
protein coding gene Chr14:57813631-57972764 (+)
C3H/HeJ MGP_C3HHeJ_G0021215
protein coding gene Chr14:59533660-59700191 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021877
protein coding gene Chr14:61993394-62165667 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019417
protein coding gene Chr14:55804769-55961142 (+)
CAST/EiJ MGP_CASTEiJ_G0020732
protein coding gene Chr14:56018361-56181309 (+)
CBA/J MGP_CBAJ_G0021182
protein coding gene Chr14:63858031-64029075 (+)
DBA/2J MGP_DBA2J_G0021305
protein coding gene Chr14:57528140-57685699 (+)
FVB/NJ MGP_FVBNJ_G0021284
protein coding gene Chr14:56925752-57083993 (+)
LP/J MGP_LPJ_G0021380
protein coding gene Chr14:60257952-60421916 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0021313
protein coding gene Chr14:63012975-63179464 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021900
protein coding gene Chr14:59059031-59224310 (+)
PWK/PhJ MGP_PWKPhJ_G0020476
protein coding gene Chr14:54228402-54388151 (+)
SPRET/EiJ MGP_SPRETEiJ_G0020309
protein coding gene Chr14:55030336-55194996 (+)
WSB/EiJ MGP_WSBEiJ_G0020785
protein coding gene Chr14:59380033-59542701 (+)



Homology
more
  • Human Ortholog
    KIF13B, kinesin family member 13B
  • Vertebrate Orthologs
    10
  • Human Ortholog
    KIF13B, kinesin family member 13B
    Orthology source: HomoloGene, HGNC
  • Synonyms
    GAKIN
  • Links
    NCBI Gene ID: 23303
    neXtProt AC: NX_Q9NQT8
    UniProt: Q9NQT8

  • Chr Location
    8p12; chr8:29067278-29263384 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 9073
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: KIF13B
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit increased circulating cholesterol and factor VIII levels.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 16554 NCBI Gene Model | MGI Sequence Detail 157129 C57BL/6J ±  kb
    transcript NM_001081177 RefSeq | MGI Sequence Detail 5603 Not Specified  
    polypeptide NP_001074646 RefSeq | MGI Sequence Detail 1843 Not Specified  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 41
      Genomic 1
      cDNA 40

      Microarray probesets 6
    Other
    Accession IDs
    less
    MGI:1924355, MGI:2145641
    References
    more
    • Summaries
      All 41
      Developmental Gene Expression 1
      Gene Ontology 5
      Phenotypes 13
    • Earliest
      J:42822 Nakagawa T, et al., Identification and classification of 16 new kinesin superfamily (KIF) proteins in mouse genome. Proc Natl Acad Sci U S A. 1997 Sep 2;94(18):9654-9
    • Latest
      J:232397 Noseda R, et al., Kif13b Regulates PNS and CNS Myelination through the Dlg1 Scaffold. PLoS Biol. 2016 Apr;14(4):e1002440

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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    last database update
    11/13/2018
    MGI 6.13
    The Jackson Laboratory