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Kif13b Gene Detail
Summary
  • Symbol
    Kif13b
  • Name
    kinesin family member 13B
  • Synonyms
    5330429L19Rik, C130021D12Rik, GAKIN, N-3 kinesin
  • Feature Type
    protein coding gene
  • IDs
    MGI:1098265
    NCBI Gene: 16554
Location & Maps
more
  • Sequence Map
    Chr14:64652531-64806296 bp, + strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      153766 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 33.77 cM, cytoband C3
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    KIF13B, kinesin family member 13B
  • Vertebrate Orthologs
    10
  • Human Ortholog
    KIF13B, kinesin family member 13B
    Orthology source: HomoloGene, HGNC
  • Synonyms
    GAKIN
  • Links
    NCBI Gene ID: 23303
    neXtProt AC: NX_Q9NQT8

  • Chr Location
    8p12; chr8:29067278-29263304 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 9073
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: KIF13B
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    63
  • Chemically induced (other)
    1
  • Gene trapped
    57
  • Targeted
    5
  • Genomic Mutations
    1 involving Kif13b
  • Incidental Mutations
Mice homozygous for a null allele exhibit increased circulating cholesterol and factor VIII levels.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000060012 Ensembl Gene Model | MGI Sequence Detail 153766 C57BL/6J ±  kb
transcript ENSMUST00000100473 Ensembl | MGI Sequence Detail 5603 Not Applicable  
polypeptide ENSMUSP00000098041 Ensembl | MGI Sequence Detail 1843 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    749 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
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  • All nucleic 39
    cDNA 39

    Microarray probesets 6
Other
Accession IDs
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MGI:1924355, MGI:2145641
References
more
  • Summaries
    All 37
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 13
  • Earliest
    J:42822 Nakagawa T, et al., Identification and classification of 16 new kinesin superfamily (KIF) proteins in mouse genome. Proc Natl Acad Sci U S A. 1997 Sep 2;94(18):9654-9
  • Latest
    J:232397 Noseda R, et al., Kif13b Regulates PNS and CNS Myelination through the Dlg1 Scaffold. PLoS Biol. 2016 Apr;14(4):e1002440

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory