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Psmb4 Gene Detail
Summary
  • Symbol
    Psmb4
  • Name
    proteasome (prosome, macropain) subunit, beta type 4
  • Synonyms
    Pros-27
  • Feature Type
    protein coding gene
  • IDs
    MGI:1098257
    NCBI Gene: 19172
  • Gene Overview
    MyGene.info: PSMB4
Location & Maps
more
  • Sequence Map
    Chr3:94884093-94886961 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      2869 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 40.74 cM, cytoband F2
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    PSMB4, proteasome subunit beta 4
  • Vertebrate Orthologs
    10
  • Human Ortholog
    PSMB4, proteasome subunit beta 4
    Orthology source: HomoloGene
  • Synonyms
    HN3, HsN3, PROS26, PROS-26
  • Links
    NCBI Gene ID: 5692
    neXtProt AC: NX_P28070

  • Chr Location
    1q21; chr1:151399565-151401936 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
  • All Mutations and Alleles
    8
  • Chemically induced (other)
    1
  • Gene trapped
    2
  • Radiation induced
    1
  • Targeted
    4
  • Genomic Mutations
    2 involving Psmb4
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000019673 VEGA Gene Model | MGI Sequence Detail 2869 C57BL/6J ±  kb
transcript OTTMUST00000047083 VEGA | MGI Sequence Detail 1183 Not Applicable  
polypeptide OTTMUSP00000021272 VEGA | MGI Sequence Detail 264 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    32 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 340
    cDNA 340

    Microarray probesets 6
References
more
  • Summaries
    All 35
    Developmental Gene Expression 3
    Gene Ontology 6
    Phenotypes 10
  • Earliest
    J:40825 Cruz M, et al., Cloning and characterization of mouse Lmp3 cDNA, encoding a proteasome beta subunit. Gene. 1997 May 6;190(2):251-6
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory