Bpgm
Gene Detail

Symbol Name ID

Bpgm 2,3-bisphosphoglycerate mutase MGI:1098242

Feature Type

protein coding gene

Genetic Map

Chromosome 6

15.01 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr6:34476207-34505613 bp, + strand From VEGA annotation of GRCm38   29407 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:55599  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: cofactor-dependent phosphoglycerate mutase
Gene Tree: Bpgm

Human homologs

Human Homolog		BPGM, 2,3-bisphosphoglycerate mutase
NCBI Gene ID		669
neXtProt AC		NX_P07738
Human Synonyms		DPGM
Human Chr (Location)		7q33; chr7:134331531-134364568 (+)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human BPGM

Alleles and phenotypes

All alleles(5) : Targeted(1) Gene trapped(4)

Gene Ontology (GO) classifications

All GO classifications: (13 annotations)

Process	erythrocyte development, glycolysis, ...
Component	cellular_component
Function	bisphosphoglycerate 2-phosphatase activity, bisphosphoglycerate mutase activity, ...

External Resources: FuncBase

Expression

Literature Summary: (4 records)
Data Summary: Results (121)    Tissues (99)    Images (26)
Theiler Stages: 3, 22, 23, 28

Assay Type	Results
RNA in situ	117
RT-PCR	4

cDNA source data(12)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(14) cDNA(13) Primer pair(1)
Microarray probesets(5)

Other database links

VEGA Gene Model	OTTMUSG00000014784 (Evidence)
Ensembl Gene Model	ENSMUSG00000038871 (Evidence)
Entrez Gene	12183 (Evidence)
DFCI	TC1573445, TC1613497
DoTS	DT.101738607, DT.495348
NIA Mouse Gene Index	U006660
EC	3.1.3.13, 5.4.2.1, 5.4.2.4
Consensus CDS Project	CCDS19994.1
International Mouse Knockout Project Status	Bpgm

Sequences

Length	Strain/Species
genomic	OTTMUSG00000014784	VEGA Gene Model | MGI Sequence Detail	29407	C57BL/6J
transcript	OTTMUST00000035087	VEGA | MGI Sequence Detail	2220	Not Applicable
polypeptide	OTTMUSP00000015661	VEGA | MGI Sequence Detail	259	Not Applicable

All sequences(48) RefSeq(2) UniProt(5)

Polymorphisms

SNPs(171 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR013078	Histidine phosphatase superfamily, clade-1
InterPro	IPR001345	Phosphoglycerate/bisphosphoglycerate mutase, active site
InterPro	IPR005952	Phosphoglycerate mutase 1
Protein Ontology	PR:000004792	bisphosphoglycerate mutase

References

(Earliest) J:43382 Le Boulch P, et al., Molecular cloning and nucleotide sequence of murine 2,3-bisphosphoglycerate mutase cDNA. Biochem Biophys Res Commun. 1988 Oct 31;156(2):874-81
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(37)

Other accession IDs

MGI:2141391, MGI:2141531, MGI:2141777