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Bpgm
Gene Detail
 Symbol
Name
ID
Bpgm
2,3-bisphosphoglycerate mutase
MGI:1098242
Feature Type protein coding gene
Genetic Map
Chromosome 6
15.01 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr6:34476207-34505613 bp, + strand
From VEGA annotation of GRCm38

  29407 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:55599  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: cofactor-dependent phosphoglycerate mutase
Gene Tree: Bpgm

Human
homologs
Human Homolog BPGM, 2,3-bisphosphoglycerate mutase
NCBI Gene ID 669
neXtProt AC  NX_P07738
Human Synonyms  DPGM
Human Chr (Location)  7q33; chr7:134646779-134679816 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human BPGM
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(4) Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Bpgm interacts with 133 markers (Mir18, Mir18b, Mir29a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process erythrocyte development, glycolytic process, ...
Component extracellular vesicular exosome
Function bisphosphoglycerate 2-phosphatase activity, bisphosphoglycerate mutase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (119)    Tissues (97)    Images (26)
Theiler Stages: 3, 22, 23, 28
Assay TypeResults
RNA in situ 117
RT-PCR 2
cDNA source data(12)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(14) cDNA(13) Primer pair(1)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000014784 (Evidence)
Ensembl Gene ModelENSMUSG00000038871 (Evidence)
Entrez Gene12183 (Evidence)
DFCITC1573445, TC1613497
DoTSDT.101738607, DT.495348
NIA Mouse Gene IndexU006660
EC3.1.3.13, 5.4.2.11, 5.4.2.4
Consensus CDS ProjectCCDS19994.1
International Mouse Knockout Project StatusBpgm
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000014784 VEGA Gene Model | MGI Sequence Detail 29407 C57BL/6J ±  kb
transcript OTTMUST00000035087 VEGA | MGI Sequence Detail 2220 Not Applicable 
polypeptide OTTMUSP00000015661 VEGA | MGI Sequence Detail 259 Not Applicable 

For the selected sequences
All sequences(50) RefSeq(4) UniProt(5)
Polymorphisms SNPs within 2kb(213 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR013078 Histidine phosphatase superfamily, clade-1
InterPro IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site
InterPro IPR005952 Phosphoglycerate mutase 1
Protein Ontology PR:000004792 bisphosphoglycerate mutase
References (Earliest) J:43382 Le Boulch P, et al., Molecular cloning and nucleotide sequence of murine 2,3-bisphosphoglycerate mutase cDNA. Biochem Biophys Res Commun. 1988 Oct 31;156(2):874-81
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(38)
Other
accession IDs
MGI:2141391, MGI:2141531, MGI:2141777

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory