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Kif16b Gene Detail
Summary
  • Symbol
    Kif16b
  • Name
    kinesin family member 16B
  • Synonyms
    8430434E15Rik, mKIAA1590, N-3 kinesin
  • Feature Type
    protein coding gene
  • IDs
    MGI:1098240
    NCBI Gene: 16558
  • Gene Overview
    MyGene.info: KIF16B
Location & Maps
more
  • Sequence Map
    Chr2:142617474-142901531 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      284058 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 70.67 cM, cytoband G3
  • Mapping Data
    4 experiments
Homology
more
  • Human Ortholog
    KIF16B, kinesin family member 16B
  • Vertebrate Orthologs
    6
  • Human Ortholog
    KIF16B, kinesin family member 16B
    Orthology source: HGNC, HomoloGene
  • Synonyms
    C20orf23, KISC20ORF, SNX23
  • Links
    NCBI Gene ID: 55614
    neXtProt AC: NX_Q96L93

  • Chr Location
    20p11.23; chr20:16272097-16573434 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    18
  • Chemically induced (other)
    1
  • Gene trapped
    14
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Kif16b
  • Incidental Mutations
Chimera embryos containing a knock-out allele and derived from tetraploid rescue exhibit lethal growth arrest at the blastocyst stage with abnormal development of the primitive endoderm, epiblast epithelium, and basement membrane.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000015608 VEGA Gene Model | MGI Sequence Detail 284058 C57BL/6J ±  kb
transcript OTTMUST00000037069 VEGA | MGI Sequence Detail 6383 Not Applicable  
polypeptide OTTMUSP00000016623 VEGA | MGI Sequence Detail 1312 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    2467 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
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  • All nucleic 12
    cDNA 12

    Microarray probesets 6
Other
Accession IDs
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MGI:1918790, MGI:2139053, MGI:2139499, MGI:2139511, MGI:3034217
References
more
  • Summaries
    All 37
    Gene Ontology 5
    Phenotypes 9
  • Earliest
    J:18490 Winter H, et al., Sequence and expression of murine type I hair keratins mHa2 and mHa3. Exp Cell Res. 1994 Jun;212(2):190-200
  • Latest
    J:221337 Farkhondeh A, et al., Characterizing KIF16B in neurons reveals a novel intramolecular "stalk inhibition" mechanism that regulates its capacity to potentiate the selective somatodendritic localization of early endosomes. J Neurosci. 2015 Mar 25;35(12):5067-86

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory