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Kif6 Gene Detail
Summary
  • Symbol
    Kif6
  • Name
    kinesin family member 6
  • Synonyms
    D130004B10Rik, D130084M03Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1098238
    NCBI Gene: 319991
  • Gene Overview
    MyGene.info: KIF6
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:49615136-49909847 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 25.78 cM, cytoband C
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2541 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1098238
protein coding gene Chr17:49615103-49909847 (.)
129S1/SvImJ MGP_129S1SvImJ_G0023879
protein coding gene Chr17:50986219-51299914 (+)
A/J MGP_AJ_G0023839
protein coding gene Chr17:49614073-49914947 (+)
AKR/J MGP_AKRJ_G0023807
protein coding gene Chr17:50141523-50462314 (+)
BALB/cJ MGP_BALBcJ_G0023841
protein coding gene Chr17:49529388-49829115 (+)
C3H/HeJ MGP_C3HHeJ_G0023604
protein coding gene Chr17:50834218-51154221 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024284
protein coding gene Chr17:53092360-53403854 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021733
protein coding gene Chr17:46347746-46639496 (+)
CAST/EiJ MGP_CASTEiJ_G0023086
protein coding gene Chr17:51052455-51374501 (+)
CBA/J MGP_CBAJ_G0023580
protein coding gene Chr17:55028420-55375660 (+)
DBA/2J MGP_DBA2J_G0023709
protein coding gene Chr17:48373382-48676620 (+)
FVB/NJ MGP_FVBNJ_G0023675
protein coding gene Chr17:48053320-48364442 (+)
LP/J MGP_LPJ_G0023789
protein coding gene Chr17:51701977-52014971 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023703
protein coding gene Chr17:54422091-54740565 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024330
protein coding gene Chr17:50474460-50785547 (+)
PWK/PhJ MGP_PWKPhJ_G0022831
protein coding gene Chr17:47826824-48129198 (+)
SPRET/EiJ MGP_SPRETEiJ_G0022645
protein coding gene Chr17:47395103-47713539 (+)
WSB/EiJ MGP_WSBEiJ_G0023150
protein coding gene Chr17:51068289-51384855 (+)



Homology
more
  • Human Ortholog
    KIF6, kinesin family member 6
  • Vertebrate Orthologs
    9
  • Human Ortholog
    KIF6, kinesin family member 6
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C6orf102, dJ1043E3.1, dJ137F1.4, dJ188D3.1
  • Links
    NCBI Gene ID: 221458
    neXtProt AC: NX_Q6ZMV9
    UniProt: Q6ZMV9

  • Chr Location
    6p21.2; chr6:39335100-39725405 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 35308
    1 human;1 mouse;1 rat;1 chimpanzee;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: KIF6
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    4 phenotype references
Mice homozgyos for an ENU-induced allele exhibit normal exercise capacity and cardiac function.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000023999 Ensembl Gene Model | MGI Sequence Detail 294712 C57BL/6J ±  kb
transcript ENSMUST00000162854 Ensembl | MGI Sequence Detail 3528 Not Applicable  
polypeptide ENSMUSP00000124674 Ensembl | MGI Sequence Detail 802 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    5 Sequences
  • InterPro Domains
    IPR027640 Kinesin-like protein
    IPR001752 Kinesin motor domain
    IPR019821 Kinesin motor domain, conserved site
    IPR036961 Kinesin motor domain superfamily
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
    IPR031852 Spindle pole body-associated protein Vik1/Cik1, microtubule binding domain
Molecular
Reagents
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  • All nucleic 9
    cDNA 9

    Microarray probesets 5
Other
Accession IDs
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MGI:2443122, MGI:3045267
References
more
  • Summaries
    All 28
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 4
  • Earliest
    J:18490 Winter H, et al., Sequence and expression of murine type I hair keratins mHa2 and mHa3. Exp Cell Res. 1994 Jun;212(2):190-200
  • Latest
    J:199830 Falnikar A, et al., Polarity in migrating neurons is related to a mechanism analogous to cytokinesis. Curr Biol. 2013 Jul 8;23(13):1215-20

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory