About   Help   FAQ
Resp18 Gene Detail
Summary
  • Symbol
    Resp18
  • Name
    regulated endocrine-specific protein 18
  • Feature Type
    protein coding gene
  • IDs
    MGI:1098222
    NCBI Gene: 19711
Location & Maps
more
  • Sequence Map
    Chr1:75272199-75278415 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      6217 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 38.65 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    RESP18, regulated endocrine specific protein 18
  • Vertebrate Orthologs
    6
  • Human Ortholog
    RESP18, regulated endocrine specific protein 18
    Orthology source: HomoloGene
  • Links
    NCBI Gene ID: 389075
    neXtProt AC: NX_Q5W5W9

  • Chr Location
    2q35; chr2:219327409-219336785 (-)  GRCh38.p2

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 2 alleles in 2 genetic backgrounds
    21 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    7
  • Chemically induced (other)
    1
  • Radiation induced
    2
  • Spontaneous
    1
  • Targeted
    3
  • Genomic Mutations
    4 involving Resp18
  • Incidental Mutations
Mice homozygous for a knock-out allele die prior to E9.5.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000024507 VEGA Gene Model | MGI Sequence Detail 6217 C57BL/6J ±  kb
transcript OTTMUST00000060135 VEGA | MGI Sequence Detail 748 Not Applicable  
polypeptide OTTMUSP00000029324 VEGA | MGI Sequence Detail 175 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    64 from dbSNP Build 142
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000013893 regulated endocrine-specific protein 18
  • InterPro Domains
    IPR024833 Regulated endocrine-specific protein 18
    IPR029403 RESP18 domain
Molecular
Reagents
less
  • All nucleic 24
    cDNA 22
    Primer pair 2

    Microarray probesets 3
Other
Accession IDs
less
MGI:2146088
References
more
  • Summaries
    All 33
    Developmental Gene Expression 8
    Diseases 1
    Gene Ontology 4
    Phenotypes 21
  • Earliest
    J:43387 Bloomquist BT, et al., Regulated endocrine-specific protein-18: a short-lived novel glucocorticoid-regulated endocrine protein. Endocrinology. 1994 Dec;135(6):2714-22
  • Latest
    J:228563 Koscielny G, et al., The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/19/2016
MGI 6.04
The Jackson Laboratory