About   Help   FAQ
Ankrd1
Gene Detail
 Symbol
Name
ID
Ankrd1
ankyrin repeat domain 1 (cardiac muscle)
MGI:1097717
Synonyms Alrp, CARP, Crap, MARP1
Feature Type protein coding gene
Genetic Map
Chromosome 19
30.52 cM, cytoband C3
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr19:36111965-36119844 bp, - strand
From NCBI annotation of GRCm38

  7880 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:8289  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Ankrd1

Human
homologs
Human Homolog ANKRD1, ankyrin repeat domain 1 (cardiac muscle)
NCBI Gene ID 27063
neXtProt AC  NX_Q15327
Human Synonyms  ALRP, bA320F15.2, C-193, CARP, CVARP, MCARP
Human Chr (Location)  10q23.31; chr10:90912100-90921275 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Targeted(5)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Ankrd1 interacts with 160 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (40 annotations)
Process cardiac muscle tissue morphogenesis, cellular response to drug, ...
Component cytoplasm, cytosol, ...
Function DNA binding, histone deacetylase binding, ...
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
Literature Summary: (20 records)
Data Summary: Results (76)    Tissues (18)    Images (34)
Theiler Stages: 11, 12, 15, 17, 19, 21, 22, 23
Assay TypeResults
RNA in situ 74
RT-PCR 2
cDNA source data(50)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(55) Genomic(2) cDNA(51) Primer pair(1) Other(1)
Microarray probesets(4)
Other database
links
Ensembl Gene ModelENSMUSG00000024803 (Evidence)
Entrez Gene107765 (Evidence)
UniGene10279
DFCITC1577982
DoTSDT.533462
NIA Mouse Gene IndexU038994
Consensus CDS ProjectCCDS29771.1
International Mouse Knockout Project StatusAnkrd1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 107765 NCBI Gene Model | MGI Sequence Detail 7880 C57BL/6J ±  kb
transcript NM_013468 RefSeq | MGI Sequence Detail 1765 C57BL/6 
polypeptide Q9CR42 UniProt | EBI | MGI Sequence Detail 319 Not Applicable 

For the selected sequences
All sequences(19) RefSeq(2) UniProt(1)
Polymorphisms SNPs within 2kb(65 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002110 Ankyrin repeat
InterPro IPR020683 Ankyrin repeat-containing domain
Protein Ontology PR:000004040 ankyrin repeat domain-containing protein 1
Graphical View of Protein Domain Structure
References (Earliest) J:38866 Zou Y, et al., CARP, a cardiac ankyrin repeat protein, is downstream in the Nkx2-5 homeobox gene pathway. Development. 1997 Feb;124(4):793-804
(Latest) J:206713 Buck D, et al., Removal of immunoglobulin-like domains from titin's spring segment alters titin splicing in mouse skeletal muscle and causes myopathy. J Gen Physiol. 2014 Feb;143(2):215-30
All references(55)
Other
accession IDs
MGD-MRK-39620, MGI:109621

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/09/2014
MGI 5.19
The Jackson Laboratory