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Rem1 Gene Detail
Summary
  • Symbol
    Rem1
  • Name
    rad and gem related GTP binding protein 1
  • Synonyms
    E030011C07Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1097696
    NCBI Gene: 19700
Location & Maps
more
  • Sequence Map
    Chr2:152626951-152635198 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      8248 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 75.41 cM, cytoband H2
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    REM1, RRAD and GEM like GTPase 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    REM1, RRAD and GEM like GTPase 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    GD:REM, GES
  • Links
    NCBI Gene ID: 28954
    neXtProt AC: NX_O75628

  • Chr Location
    20q11.21; chr20:31475288-31484905 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    4
  • Chemically induced (other)
    1
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Rem1
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000015816 VEGA Gene Model | MGI Sequence Detail 8248 C57BL/6J ±  kb
transcript OTTMUST00000037607 VEGA | MGI Sequence Detail 1663 Not Applicable  
polypeptide OTTMUSP00000016855 VEGA | MGI Sequence Detail 297 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    116 from dbSNP Build 142
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000013881 GTP-binding protein REM 1
  • InterPro Domains
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
    IPR001806 Small GTPase superfamily
    IPR017358 Small GTPase superfamily, GEM/REM/Rad
    IPR020849 Small GTPase superfamily, Ras type
    IPR005225 Small GTP-binding protein domain
Molecular
Reagents
less
  • All nucleic 21
    cDNA 21

    Microarray probesets 4
Other
Accession IDs
less
MGI:2442578
References
more
  • Summaries
    All 26
    Developmental Gene Expression 3
    Gene Ontology 2
    Phenotypes 5
  • Earliest
    J:42600 Finlin BS, et al., Rem is a new member of the Rad- and Gem/Kir Ras-related GTP-binding protein family repressed by lipopolysaccharide stimulation. J Biol Chem. 1997 Aug 29;272(35):21982-8
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
09/27/2016
MGI 6.05
The Jackson Laboratory