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Pold2
Gene Detail
Symbol

Name
ID
Pold2
polymerase (DNA directed), delta 2, regulatory subunit
MGI:1097163
Synonyms
50kDa, p50, po1D2
Feature Type
protein coding gene
Genetic Map
Chromosome 11
3.88 cM, cytoband A2
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr11:5872180-5878292 bp, - strand
From VEGA annotation of GRCm38

  6113 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:4538  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: DNA-directed DNA polymerase delta regulatory chain
Gene Tree: Pold2

Human
homologs
Human Homolog POLD2, polymerase (DNA directed), delta 2, accessory subunit
NCBI Gene ID 5425
neXtProt AC  NX_P49005
Human Chr (Location)  7p13; chr7:44114680-44123570 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(18) : Gene trapped(14) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Pold2 interacts with 21 markers (Mir135a-1, Mir135a-2, Mir135b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process DNA biosynthetic process, DNA-dependent DNA replication, ...
Component delta DNA polymerase complex, nucleoplasm, ...
Function DNA binding, DNA-directed DNA polymerase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (94)    Tissues (94)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 94
cDNA source data(94)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(94) cDNA(94)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000005094 (Evidence)
Ensembl Gene ModelENSMUSG00000020471 (Evidence)
Entrez Gene18972 (Evidence)
UniGene35788
DFCITC1575325
NIA Mouse Gene IndexU032476
EC2.7.7.7
Consensus CDS ProjectCCDS24407.1
International Mouse Knockout Project StatusPold2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005094 VEGA Gene Model | MGI Sequence Detail 6113 C57BL/6J ±  kb
transcript OTTMUST00000011387 VEGA | MGI Sequence Detail 1646 Not Applicable 
polypeptide OTTMUSP00000005307 VEGA | MGI Sequence Detail 469 Not Applicable 

For the selected sequences
All sequences(37) RefSeq(4) UniProt(3)
Polymorphisms
SNPs within 2kb(36 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR007185 DNA polymerase alpha/epsilon, subunit B
InterPro IPR024826 DNA polymerase delta/II small subunit family
Protein Ontology PR:000012964 DNA polymerase delta subunit 2
References
(Earliest) J:42588 Hindges R, et al., Cloning, chromosomal localization, and interspecies interaction of mouse DNA polymerase delta small subunit (PolD2). Genomics. 1997 Aug 15;44(1):45-51
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(35)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory