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Ppef1 Gene Detail
Summary
  • Symbol
    Ppef1
  • Name
    protein phosphatase with EF hand calcium-binding domain 1
  • Synonyms
    Dres10, PPEF 1, PPEF-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1097157
    NCBI Gene: 237178
  • Gene Overview
    MyGene.info: PPEF1
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:160623094-160735765 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome X, 73.95 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    369 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1097157
protein coding gene ChrX:160622419-160751290 (-)
129S1/SvImJ MGP_129S1SvImJ_G0036232
protein coding gene ChrX:158554349-158658288 (-)
A/J MGP_AJ_G0036202
protein coding gene ChrX:157806251-157916765 (-)
AKR/J MGP_AKRJ_G0036130
protein coding gene ChrX:162817922-162928397 (-)
BALB/cJ MGP_BALBcJ_G0036195
protein coding gene ChrX:155887263-155996411 (-)
C3H/HeJ MGP_C3HHeJ_G0035901
protein coding gene ChrX:158952137-159064423 (-)
C57BL/6NJ MGP_C57BL6NJ_G0036717
protein coding gene ChrX:163275514-163388772 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0033539
protein coding gene ChrX:149035885-149147701 (-)
CAST/EiJ MGP_CASTEiJ_G0035190
protein coding gene ChrX:137966871-138089362 (-)
CBA/J MGP_CBAJ_G0035876
protein coding gene ChrX:167913560-168038822 (-)
DBA/2J MGP_DBA2J_G0036042
protein coding gene ChrX:156774576-156880580 (-)
FVB/NJ MGP_FVBNJ_G0035973
protein coding gene ChrX:155884902-155997239 (-)
LP/J MGP_LPJ_G0036127
protein coding gene ChrX:159731331-159841519 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0036005
protein coding gene ChrX:176627478-176756603 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0036758
protein coding gene ChrX:158102475-158211712 (-)
PWK/PhJ MGP_PWKPhJ_G0034888
protein coding gene ChrX:134826657-134927534 (-)
SPRET/EiJ MGP_SPRETEiJ_G0034709
protein coding gene ChrX:138379060-138489842 (-)
WSB/EiJ MGP_WSBEiJ_G0035325
protein coding gene ChrX:156055329-156180882 (-)



Homology
more
  • Human Ortholog
    PPEF1, protein phosphatase with EF-hand domain 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    PPEF1, protein phosphatase with EF-hand domain 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    PP7, PPEF, PPP7C, PPP7CA
  • Links
    NCBI Gene ID: 5475
    neXtProt AC: NX_O14829
    UniProt: O14829

  • Chr Location
    Xp22.13; chrX:18675909-18827921 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    2 phenotypes from multigenic genotypes
    5 phenotype references
Homozygous null female and hemizygous null male mice are viable, fertile and display no overt abnormalities.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000062168 Ensembl Gene Model | MGI Sequence Detail 112672 C57BL/6J ±  kb
transcript ENSMUST00000071204 Ensembl | MGI Sequence Detail 2483 Not Applicable  
polypeptide ENSMUSP00000071191 Ensembl | MGI Sequence Detail 650 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    cDNA 8
    Other 1

    Microarray probesets 1
References
more
  • Summaries
    All 27
    Developmental Gene Expression 3
    Gene Ontology 6
    Phenotypes 5
  • Earliest
    J:42619 Banfi S, et al., Drosophila-related expressed sequences. Hum Mol Genet. 1997;6(10):1745-53
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory