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Wdfy3 Gene Detail
Summary
  • Symbol
    Wdfy3
  • Name
    WD repeat and FYVE domain containing 3
  • Synonyms
    2610509D04Rik, Bchs, Bwf1, D5Ertd66e, Ggtb3, mKIAA0993
  • Feature Type
    protein coding gene
  • IDs
    MGI:1096875
    NCBI Gene: 72145
  • Gene Overview
    MyGene.info: WDFY3
Location & Maps
more
  • Sequence Map
    Chr5:101832956-102069921 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      236966 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 48.95 cM
  • Mapping Data
    5 experiments
Homology
more
  • Human Ortholog
    WDFY3, WD repeat and FYVE domain containing 3
  • Vertebrate Orthologs
    10
  • Human Ortholog
    WDFY3, WD repeat and FYVE domain containing 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ALFY, ZFYVE25
  • Links
    NCBI Gene ID: 23001
    neXtProt AC: NX_Q8IZQ1

  • Chr Location
    4q21.23; chr4:84669537-84966391 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 22855
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed
  • HCOP
    human homology predictions: WDFY3
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    16 phenotype references
  • All Mutations and Alleles
    105
  • Chemically induced (ENU)
    1
  • Chemically induced (other)
    1
  • Gene trapped
    99
  • Radiation induced
    1
  • Spontaneous
    1
  • Targeted
    2
  • Genomic Mutations
    3 involving Wdfy3
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000037884 VEGA Gene Model | MGI Sequence Detail 236966 C57BL/6J ±  kb
transcript OTTMUST00000097684 VEGA | MGI Sequence Detail 10581 Not Applicable  
polypeptide OTTMUSP00000054785 VEGA | MGI Sequence Detail 3526 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    1229 from dbSNP Build 142
  • PCR
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 19
    cDNA 17
    Primer pair 2

    Microarray probesets 7
Other
Accession IDs
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MGI:1098710, MGI:1919395, MGI:2141186
References
more
  • Summaries
    All 48
    Developmental Gene Expression 5
    Gene Ontology 8
    Phenotypes 16
  • Earliest
    J:39286 Uehara K, et al., Molecular cloning and characterization of beta-1,4-galactosyltransferase expressed in mouse testis. Eur J Biochem. 1997 Mar 15;244(3):706-12
  • Latest
    J:225200 Orosco LA, et al., Loss of Wdfy3 in mice alters cerebral cortical neurogenesis reflecting aspects of the autism pathology. Nat Commun. 2014;5:4692

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory