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Bcan
Gene Detail
Symbol

Name
ID
Bcan
brevican
MGI:1096385
Synonyms
Cspg7
Feature Type
protein coding gene
Genetic Map
Chromosome 3
38.78 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr3:87987531-88000356 bp, - strand
From Ensembl annotation of GRCm38

  12826 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:7244  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Bcan

Human
homologs
Human Homolog BCAN, brevican
NCBI Gene ID 63827
neXtProt AC  NX_Q96GW7
Human Synonyms  BEHAB, CSPG7
Human Chr (Location)  1q31; chr1:156641948-156659532 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous mutation of this gene results in impaired LTP maintenance, but mutant animals show normal behavior and spatial learning capabilities.
 
Interactions
Bcan interacts with 67 markers (Mir19b-1, Mir19b-2, Mir23a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process cell adhesion, hippocampus development
Component anchored component of membrane, dendrite, ...
Function carbohydrate binding, hyaluronic acid binding
External Resources: FuncBase
Expression
Literature Summary: (14 records)
Data Summary: Results (281)    Tissues (115)    Images (41)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 273
Northern blot 8
cDNA source data(24)
External Resources: Allen Institute   GENSAT   GEO   Expression Atlas
Molecular
reagents
All nucleic(28) Genomic(1) cDNA(25) Primer pair(2)
Microarray probesets(5)
Other database
links
Ensembl Gene ModelENSMUSG00000004892 (Evidence)
Entrez Gene12032 (Evidence)
UniGene4598
DFCITC1705901, TC1703272, TC1577609
DoTSDT.484564, DT.91286130, DT.91377708
NIA Mouse Gene IndexU024239
Consensus CDS ProjectCCDS17462.1
International Mouse Knockout Project StatusBcan
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000004892 Ensembl Gene Model | MGI Sequence Detail 12826 C57BL/6J ±  kb
transcript ENSMUST00000090971 Ensembl | MGI Sequence Detail 3267 Not Applicable 
polypeptide ENSMUSP00000088491 Ensembl | MGI Sequence Detail 883 Not Applicable 

For the selected sequences
All sequences(35) RefSeq(10) UniProt(5)
Polymorphisms
SNPs within 2kb(80 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001304 C-type lectin
InterPro IPR018378 C-type lectin, conserved site
InterPro IPR016187 C-type lectin fold
InterPro IPR016186 C-type lectin-like
InterPro IPR013032 EGF-like, conserved site
InterPro IPR000742 Epidermal growth factor-like domain
InterPro IPR007110 Immunoglobulin-like domain
InterPro IPR013783 Immunoglobulin-like fold
InterPro IPR003006 Immunoglobulin/major histocompatibility complex, conserved site
InterPro IPR013106 Immunoglobulin V-set
InterPro IPR003596 Immunoglobulin V-set, subgroup
InterPro IPR000538 Link
InterPro IPR000436 Sushi/SCR/CCP
Protein Ontology PR:000004673 brevican core protein
References
(Earliest) J:42589 Rauch U, et al., Sequence and chromosomal localization of the mouse brevican gene. Genomics. 1997 Aug 15;44(1):15-21
(Latest) J:205051 Miller JA, et al., Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates. Development. 2013 Nov;140(22):4633-44
All references(48)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/11/2014
MGI 5.20
The Jackson Laboratory