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Bcan
Gene Detail
Symbol

Name
ID
Bcan
brevican
MGI:1096385
Synonyms
Cspg7
Feature Type
protein coding gene
Genetic Map
Chromosome 3
38.78 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr3:87987531-88000230 bp, - strand
From VEGA annotation of GRCm38

  12700 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:7244  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: BCAN
Gene Tree: Bcan

Human
homologs
BCAN, brevican
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 63827
neXtProt AC: NX_Q96GW7

Human Synonyms: BEHAB, CSPG7

Human Chr (Location): 1q31; chr1:156641948-156659532 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous mutation of this gene results in impaired LTP maintenance, but mutant animals show normal behavior and spatial learning capabilities.
 
Interactions
Bcan interacts with 67 markers (Mir19b-1, Mir19b-2, Mir23a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process cell adhesion, central nervous system development, ...
Component anchored component of membrane, dendrite, ...
Function carbohydrate binding, hyaluronic acid binding
External Resources: FuncBase
Expression
Literature Summary: (15 records)
Data Summary: Results (281)    Tissues (115)    Images (41)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 273
Northern blot 8
cDNA source data(24)
Other mouse links: Allen Institute   GENSAT   GEO   Expression Atlas
Other vertebrate links: GEISHA BCAN ZFIN bcan    NEW 
Molecular
reagents
All nucleic(28) Genomic(1) cDNA(25) Primer pair(2)
Microarray probesets(5)
Other database
links
VEGA Gene Model OTTMUSG00000051892 (Evidence)
Ensembl Gene Model ENSMUSG00000004892 (Evidence)
Entrez Gene 12032 (Evidence)
UniGene 4598
DFCI TC1577609, TC1703272, TC1705901
DoTS DT.484564, DT.91286130, DT.91377708
NIA Mouse Gene Index U024239
Consensus CDS Project CCDS17462.1
International Mouse Phenotyping Consortium Status Bcan
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000051892 VEGA Gene Model | MGI Sequence Detail 12700 C57BL/6J ±  kb
transcript OTTMUST00000130659 VEGA | MGI Sequence Detail 3141 Not Applicable 
polypeptide OTTMUSP00000069996 VEGA | MGI Sequence Detail 883 Not Applicable 

For the selected sequences
All sequences(47) RefSeq(8) UniProt(4)
Polymorphisms
SNPs within 2kb(80 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001304 C-type lectin
InterPro IPR018378 C-type lectin, conserved site
InterPro IPR016187 C-type lectin fold
InterPro IPR016186 C-type lectin-like
InterPro IPR013032 EGF-like, conserved site
InterPro IPR000742 EGF-like domain
InterPro IPR007110 Immunoglobulin-like domain
InterPro IPR013783 Immunoglobulin-like fold
InterPro IPR003006 Immunoglobulin/major histocompatibility complex, conserved site
InterPro IPR013106 Immunoglobulin V-set domain
InterPro IPR000538 Link domain
InterPro IPR000436 Sushi/SCR/CCP domain
Protein Ontology PR:000004673 brevican core protein
References
(Earliest) J:42589 Rauch U, et al., Sequence and chromosomal localization of the mouse brevican gene. Genomics. 1997 Aug 15;44(1):15-21
(Latest) J:219896 Zhang A, et al., Neurofascin 140 is an embryonic neuronal neurofascin isoform that promotes the assembly of the node of Ranvier. J Neurosci. 2015 Feb 4;35(5):2246-54
All references(49)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory