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Galr1 Gene Detail
Summary
  • Symbol
    Galr1
  • Name
    galanin receptor 1
  • Synonyms
    Galnr1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1096364
    NCBI Gene: 14427
  • Gene Overview
    MyGene.info: GALR1
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr18:82392496-82406777 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 18, 55.78 cM, cytoband E3-E4
  • Mapping Data
    6 experiments
Strain
Comparison
more
  • SNPs within 2kb
    47 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1096364
protein coding gene Chr18:82392496-82406777 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024600
protein coding gene Chr18:83413560-83427845 (-)
A/J MGP_AJ_G0024567
protein coding gene Chr18:79771847-79786126 (-)
AKR/J MGP_AKRJ_G0024538
protein coding gene Chr18:82136849-82151130 (-)
BALB/cJ MGP_BALBcJ_G0024565
protein coding gene Chr18:79962210-79976489 (-)
C3H/HeJ MGP_C3HHeJ_G0024334
protein coding gene Chr18:82246251-82260588 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025012
protein coding gene Chr18:85471648-85485928 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022443
protein coding gene Chr18:78532151-78546443 (-)
CAST/EiJ MGP_CASTEiJ_G0023807
protein coding gene Chr18:82545206-82565420 (-)
CBA/J MGP_CBAJ_G0024304
protein coding gene Chr18:88653689-88667959 (-)
DBA/2J MGP_DBA2J_G0024434
protein coding gene Chr18:79296169-79310449 (-)
FVB/NJ MGP_FVBNJ_G0024400
protein coding gene Chr18:78603540-78617892 (-)
LP/J MGP_LPJ_G0024518
protein coding gene Chr18:83236639-83250956 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024430
protein coding gene Chr18:89878186-89892441 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025061
protein coding gene Chr18:82311736-82326024 (-)
PWK/PhJ MGP_PWKPhJ_G0023552
protein coding gene Chr18:79663777-79683896 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023358
protein coding gene Chr18:82423841-82438462 (-)
WSB/EiJ MGP_WSBEiJ_G0023869
protein coding gene Chr18:82291093-82305407 (-)



Homology
more
  • Human Ortholog
    GALR1, galanin receptor 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    GALR1, galanin receptor 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    GALNR, GALNR1
  • Links
    NCBI Gene ID: 2587
    neXtProt AC: NX_P47211
    UniProt: P47211

  • Chr Location
    18q23; chr18:77250052-77270142 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotypes from 2 alleles in 3 genetic backgrounds
    23 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Homozygous mutation of this gene does not appear to result in a phenotype.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 14427 NCBI Gene Model | MGI Sequence Detail 14282 C57BL/6J ±  kb
transcript NM_008082 RefSeq | MGI Sequence Detail 2871 C57BL/6  
polypeptide P56479 UniProt | EBI | MGI Sequence Detail 348 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 12
    Genomic 2
    cDNA 9
    Primer pair 1

    Microarray probesets 4
References
more
  • Summaries
    All 65
    Developmental Gene Expression 7
    Gene Ontology 7
    Phenotypes 23
  • Earliest
    J:38577 Simoneaux DK, et al., Galanin receptor gene (Galnr1) is tightly linked to the myelin basic protein gene on Chromosome 18 in mouse. Mamm Genome. 1997;8(Nov):875
  • Latest
    J:240526 Hall EA, et al., PLAA Mutations Cause a Lethal Infantile Epileptic Encephalopathy by Disrupting Ubiquitin-Mediated Endolysosomal Degradation of Synaptic Proteins. Am J Hum Genet. 2017 May 4;100(5):706-724

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory