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Galr1 Gene Detail
Summary
  • Symbol
    Galr1
  • Name
    galanin receptor 1
  • Synonyms
    Galnr1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1096364
    NCBI Gene: 14427
  • Gene Overview
    MyGene.info: GALR1
Location & Maps
more
  • Sequence Map
    Chr18:82392496-82406777 bp, - strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      14282 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 18, 55.78 cM, cytoband E3-E4
  • Mapping Data
    6 experiments
Homology
more
  • Human Ortholog
    GALR1, galanin receptor 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    GALR1, galanin receptor 1
    Orthology source: HGNC, HomoloGene
  • Synonyms
    GALNR, GALNR1
  • Links
    NCBI Gene ID: 2587
    neXtProt AC: NX_P47211

  • Chr Location
    18q23; chr18:77250052-77270142 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotypes from 2 alleles in 3 genetic backgrounds
    22 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    5
  • Targeted
    4
  • Transposon induced
    1
  • Genomic Mutations
    1 involving Galr1
  • Incidental Mutations
Homozygous mutation of this gene does not appear to result in a phenotype.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 14427 NCBI Gene Model | MGI Sequence Detail 14282 C57BL/6J ±  kb
transcript NM_008082 RefSeq | MGI Sequence Detail 2871 C57BL/6  
polypeptide P56479 UniProt | EBI | MGI Sequence Detail 348 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    47 from dbSNP Build 142
  • RFLP
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 12
    Genomic 2
    cDNA 7
    Primer pair 1
    Other 2

    Microarray probesets 4
References
more
  • Summaries
    All 54
    Developmental Gene Expression 5
    Gene Ontology 6
    Phenotypes 22
  • Earliest
    J:38577 Simoneaux DK, et al., Galanin receptor gene (Galnr1) is tightly linked to the myelin basic protein gene on Chromosome 18 in mouse. Mamm Genome. 1997;8(Nov):875
  • Latest
    J:231842 Kerr N, et al., The generation of knock-in mice expressing fluorescently tagged galanin receptors 1 and 2. Mol Cell Neurosci. 2015 Sep;68:258-71

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory