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Galr1
Gene Detail
Symbol

Name
ID
Galr1
galanin receptor 1
MGI:1096364
Synonyms
Galnr1
Feature Type
protein coding gene
Genetic Map
Chromosome 18
55.78 cM, cytoband E3-E4
Detailed Genetic Map ± 1 cM


Mapping data(6)
Sequence Map
Chr18:82392496-82406777 bp, - strand
From NCBI annotation of GRCm38

  14282 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:74396  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: GALR1
Protein SuperFamily: galanin receptor
Gene Tree: Galr1

Human
homologs
GALR1, galanin receptor 1
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 2587
neXtProt AC: NX_P47211

Human Synonyms: GALNR, GALNR1

Human Chr (Location): 18q23; chr18:77250052-77270142 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous mutation of this gene does not appear to result in a phenotype.
 
Interactions
Galr1 interacts with 192 markers (Mir1a-1, Mir1a-2, Mir9-1, ...)
Expression
Literature Summary: (5 records)
Data Summary: Results (102)    Tissues (51)    Images (12)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 14
In situ reporter (knock in) 50
RT-PCR 38
cDNA source data(6)
Other mouse links: Allen Institute   GENSAT   GEO   Expression Atlas
Other vertebrate links: Xenbase galr1    NEW 
Molecular
reagents
All nucleic(12) Genomic(2) cDNA(7) Primer pair(1) Other(2)
Microarray probesets(4)
Other database
links
Ensembl Gene Model ENSMUSG00000024553 (Evidence)
Entrez Gene 14427 (Evidence)
UniGene 6219
DFCI TC1651929, TC1591802
DoTS DT.87058890, DT.91354952
NIA Mouse Gene Index U038619
Consensus CDS Project CCDS29372.1
International Mouse Phenotyping Consortium Status Galr1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 14427 NCBI Gene Model | MGI Sequence Detail 14282 C57BL/6J ±  kb
transcript NM_008082 RefSeq | MGI Sequence Detail 2871 C57BL/6 
polypeptide P56479 UniProt | EBI | MGI Sequence Detail 348 Not Applicable 

For the selected sequences
All sequences(22) RefSeq(2) UniProt(1)
Polymorphisms
RFLP(1) : SNPs within 2kb(47 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR003906 Galanin receptor 1
InterPro IPR000405 Galanin receptor family
InterPro IPR017452 GPCR, rhodopsin-like, 7TM
InterPro IPR000276 G protein-coupled receptor, rhodopsin-like
Protein Ontology PR:000001585 galanin receptor type 1
Graphical View of Protein Domain Structure
References
(Earliest) J:38577 Simoneaux DK, et al., Galanin receptor gene (Galnr1) is tightly linked to the myelin basic protein gene on Chromosome 18 in mouse. Mamm Genome. 1997;8(Nov):875
(Latest) J:214920 Einstein EB, et al., Galanin-induced decreases in nucleus accumbens/striatum excitatory postsynaptic potentials and morphine conditioned place preference require both galanin receptor 1 and galanin receptor 2. Eur J Neurosci. 2013 May;37(9):1541-9
All references(56)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/30/2015
MGI 5.22
The Jackson Laboratory