Fgfbp1
Gene Detail

Symbol Name ID

Fgfbp1 fibroblast growth factor binding protein 1 MGI:1096350

Synonyms

FGF-BP

Feature Type

protein coding gene

Genetic Map

Chromosome 5

23.95 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr5:43978865-43981762 bp, - strand From Ensembl annotation of GRCm38   2898 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:3766  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: fibroblast growth factor-binding protein
Gene Tree: Fgfbp1

Human homologs

Human Homolog		FGFBP1, fibroblast growth factor binding protein 1
NCBI Gene ID		9982
neXtProt AC		NX_Q14512
Human Synonyms		FGFBP, FGF-BP, FGF-BP1, FGFBP-1, HBP17
Human Chr (Location)		4p15.32; chr4:15937192-15940363 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(2) : Targeted(1) Gene trapped(1)

Gene Ontology (GO) classifications

All GO classifications: (9 annotations)

Process	cell-cell signaling, positive regulation of cell proliferation, ...
Component	cell surface, extracellular region, ...
Function	fibroblast growth factor binding, growth factor binding

External Resources: FuncBase

Expression

Literature Summary: (4 records)
Data Summary: Results (165)    Tissues (52)    Images (21)
Theiler Stages: 13, 19, 20, 21, 23, 24, 25, 28

Assay Type	Results
RNA in situ	137
Northern blot	28

cDNA source data(18)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(20) Genomic(1) cDNA(18) Primer pair(1)
Microarray probesets(4)

Other database links

Ensembl Gene Model	ENSMUSG00000048373 (Evidence)
Entrez Gene	14181 (Evidence)
UniGene	46053
DFCI	TC1584064
DoTS	DT.101234775, DT.110658646, DT.528564
Consensus CDS Project	CCDS19268.1
International Mouse Knockout Project Status	Fgfbp1

Sequences

Length	Strain/Species
genomic	ENSMUSG00000048373	Ensembl Gene Model | MGI Sequence Detail	2898	C57BL/6J
transcript	ENSMUST00000061299	Ensembl | MGI Sequence Detail	1154	Not Applicable
polypeptide	ENSMUSP00000056900	Ensembl | MGI Sequence Detail	251	Not Applicable

All sequences(21) RefSeq(4) UniProt(1)

Polymorphisms

SNPs(29 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR010510	FGF binding 1
Protein Ontology	PR:000007501	fibroblast growth factor-binding protein 1

References

(Earliest) J:4096 Madarame H, et al., Spontaneous adenocarcinoma of the colon in a DDD mouse. Lab Anim Sci. 1993 Feb;43(1):108-10
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(32)