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Fgfbp1
Gene Detail
 Symbol
Name
ID
Fgfbp1
fibroblast growth factor binding protein 1
MGI:1096350
Synonyms FGF-BP
Feature Type protein coding gene
Genetic Map
Chromosome 5
23.95 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr5:43978865-43981762 bp, - strand
From Ensembl annotation of GRCm38

  2898 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3766  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Protein SuperFamily: fibroblast growth factor-binding protein
Gene Tree: Fgfbp1

Human
homologs
Human Homolog FGFBP1, fibroblast growth factor binding protein 1
NCBI Gene ID 9982
neXtProt AC  NX_Q14512
Human Synonyms  FGFBP, FGF-BP, FGF-BP1, FGFBP-1, HBP17
Human Chr (Location)  4p15.32; chr4:15935569-15938740 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Chemically induced (ENU)(1) Gene trapped(1) Radiation induced(1) Targeted(1)
Genomic Mutations involving Fgfbp1 (2)
Incidental mutations (data from Mutagenetix )
Alleles Annotated to Human Diseases(2)   
Interactions
Fgfbp1 interacts with 61 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process cell-cell signaling, positive regulation of cell proliferation, ...
Component cell surface, extracellular region, ...
Function fibroblast growth factor binding, growth factor binding
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (223)    Tissues (109)    Images (23)
Theiler Stages: 13, 19, 20, 21, 23, 24, 25, 26, 28
Assay TypeResults
RNA in situ 195
Northern blot 28
cDNA source data(18)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(20) Genomic(1) cDNA(18) Primer pair(1)
Microarray probesets(4)
Other database
links
Ensembl Gene ModelENSMUSG00000048373 (Evidence)
Entrez Gene14181 (Evidence)
UniGene46053
DFCITC1584064
DoTSDT.101234775, DT.110658646, DT.528564
Consensus CDS ProjectCCDS19268.1
International Mouse Knockout Project StatusFgfbp1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000048373 Ensembl Gene Model | MGI Sequence Detail 2898 C57BL/6J ±  kb
transcript ENSMUST00000061299 Ensembl | MGI Sequence Detail 1154 Not Applicable 
polypeptide ENSMUSP00000056900 Ensembl | MGI Sequence Detail 251 Not Applicable 

For the selected sequences
All sequences(25) RefSeq(8) UniProt(1)
Polymorphisms SNPs within 2kb(41 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR010510 FGF binding 1
Protein Ontology PR:000007501 fibroblast growth factor-binding protein 1
References (Earliest) J:4096 Madarame H, et al., Spontaneous adenocarcinoma of the colon in a DDD mouse. Lab Anim Sci. 1993 Feb;43(1):108-10
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(33)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory