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Fgfbp1 Gene Detail
Summary
  • Symbol
    Fgfbp1
  • Name
    fibroblast growth factor binding protein 1
  • Synonyms
    FGF-BP
  • Feature Type
    protein coding gene
  • IDs
    MGI:1096350
    NCBI Gene: 14181
  • Gene Overview
    MyGene.info: FGFBP1
Location & Maps
more
  • Sequence Map
    Chr5:43978858-43981779 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      2922 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 23.95 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    FGFBP1, fibroblast growth factor binding protein 1
  • Vertebrate Orthologs
    7
  • Human Ortholog
    FGFBP1, fibroblast growth factor binding protein 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    FGFBP, FGF-BP, FGF-BP1, FGFBP-1, HBP17
  • Links
    NCBI Gene ID: 9982
    neXtProt AC: NX_Q14512

  • Chr Location
    4p15.32; chr4:15935569-15938740 (-)  GRCh38.p2

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    21 phenotype references
  • All Mutations and Alleles
    8
  • Chemically induced (ENU)
    1
  • Chemically induced (other)
    2
  • Gene trapped
    1
  • Radiation induced
    2
  • Spontaneous
    1
  • Targeted
    1
  • Genomic Mutations
    6 involving Fgfbp1
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000029016 VEGA Gene Model | MGI Sequence Detail 2922 C57BL/6J ±  kb
transcript OTTMUST00000133821 VEGA | MGI Sequence Detail 1228 Not Applicable  
polypeptide OTTMUSP00000071067 VEGA | MGI Sequence Detail 251 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    42 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000007501 fibroblast growth factor-binding protein 1
  • InterPro Domains
    IPR010510 FGF binding 1
Molecular
Reagents
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  • All nucleic 20
    Genomic 1
    cDNA 18
    Primer pair 1

    Microarray probesets 4
References
more
  • Summaries
    All 33
    Developmental Gene Expression 5
    Diseases 1
    Gene Ontology 5
    Phenotypes 21
  • Earliest
    J:4096 Madarame H, et al., Spontaneous adenocarcinoma of the colon in a DDD mouse. Lab Anim Sci. 1993 Feb;43(1):108-10
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory