Ccr10
Gene Detail

Symbol Name ID

Ccr10 chemokine (C-C motif) receptor 10 MGI:1096320

Synonyms

CCR10, Cmkbr9, GPR2

Feature Type

protein coding gene

Genetic Map

Chromosome 11

64.34 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr11:101172997-101175443 bp, - strand From VEGA annotation of GRCm38   2447 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:7271  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken

Protein SuperFamily: chemokine receptor
Gene Tree: Ccr10

Human homologs

Human Homolog		CCR10, chemokine (C-C motif) receptor 10
NCBI Gene ID		2826
neXtProt AC		NX_P46092
Human Synonyms		GPR2
Human Chr (Location)		17q21.1-q21.3; chr17:40831420-40833845 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(6) : Targeted(6)
 

Mice homozygous for null mutation are viable and fertile, without any detectable neurological abnormalities.

 

Gene Ontology (GO) classifications

All GO classifications: (18 annotations)

Process	chemokine-mediated signaling pathway, chemotaxis, ...
Component	integral to membrane, integral to plasma membrane, ...
Function	C-C chemokine binding, C-C chemokine receptor activity, ...

External Resources: FuncBase

Expression

Literature Summary: (1 records)
cDNA source data(5)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(6) cDNA(5) Other(1)
Microarray probesets(2)

Other database links

VEGA Gene Model	OTTMUSG00000002727 (Evidence)
Ensembl Gene Model	ENSMUSG00000044052 (Evidence)
Entrez Gene	12777 (Evidence)
UniGene	8021
DFCI	TC1588913
DoTS	DT.40148296
Consensus CDS Project	CCDS25454.1
International Mouse Knockout Project Status	Ccr10

Sequences

Length	Strain/Species
genomic	OTTMUSG00000002727	VEGA Gene Model | MGI Sequence Detail	2447	C57BL/6J
transcript	OTTMUST00000005413	VEGA | MGI Sequence Detail	1726	Not Applicable
polypeptide	OTTMUSP00000002576	VEGA | MGI Sequence Detail	362	Not Applicable

All sequences(18) RefSeq(2) UniProt(1)

Polymorphisms

RFLP(1) : SNPs(3 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR005382	CC chemokine receptor, type 10
InterPro	IPR000276	GPCR, rhodopsin-like
InterPro	IPR017452	GPCR, rhodopsin-like, 7TM
Protein Ontology	PR:000001198	C-C chemokine receptor type 10

References

(Earliest) J:40322 Nibbs RJB, et al., Cloning and characterization of a novel murine beta chemokine receptor, D6. Comparison to three other related macrophage inflammatory protein-1alpha receptors, CCR-1, CCR-3, and CCR-5. J Biol Chem. 1997 May 9;272(19):12495-504
(Latest) J:180099 Hu S, et al., Critical roles of chemokine receptor CCR10 in regulating memory IgA responses in intestines. Proc Natl Acad Sci U S A. 2011 Nov 8;108(45):E1035-44
All references(40)