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Ccr10
Gene Detail
Symbol

Name
ID
Ccr10
chemokine (C-C motif) receptor 10
MGI:1096320
Synonyms
CCR10, Cmkbr9, GPR2
Feature Type
protein coding gene
Genetic Map
Chromosome 11
64.34 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr11:101172997-101175443 bp, - strand
From VEGA annotation of GRCm38

  2447 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:7271  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken

HCOP human homology predictions: CCR10
Protein SuperFamily: chemokine receptor
Gene Tree: Ccr10

Human
homologs
CCR10, chemokine (C-C motif) receptor 10
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 2826
neXtProt AC: NX_P46092

Human Synonyms: GPR2

Human Chr (Location): 17q21.1-q21.3; chr17:42679402-42681827 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(7) : Targeted(7)
Genomic Mutations involving Ccr10 (1)
Incidental mutations (data from CvDC )
 
Mice homozygous for null mutation are viable and fertile, without any detectable neurological abnormalities.
 
Interactions
Ccr10 interacts with 91 markers (Mir27a, Mir27b, Mir30b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (20 annotations)
Process chemokine-mediated signaling pathway, chemotaxis, ...
Component cell, cell surface, ...
Function C-C chemokine receptor activity, chemokine receptor activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
cDNA source data(5)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: ZFIN ccr10    NEW 
Molecular
reagents
All nucleic(6) cDNA(5) Other(1)
Microarray probesets(2)
Other database
links
VEGA Gene Model OTTMUSG00000002727 (Evidence)
Ensembl Gene Model ENSMUSG00000044052 (Evidence)
Entrez Gene 12777 (Evidence)
UniGene 8021
DFCI TC1588913
DoTS DT.40148296
Consensus CDS Project CCDS25454.1
International Mouse Phenotyping Consortium Status Ccr10
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000002727 VEGA Gene Model | MGI Sequence Detail 2447 C57BL/6J ±  kb
transcript OTTMUST00000005413 VEGA | MGI Sequence Detail 1726 Not Applicable 
polypeptide OTTMUSP00000002576 VEGA | MGI Sequence Detail 362 Not Applicable 

For the selected sequences
All sequences(20) RefSeq(4) UniProt(1)
Polymorphisms
RFLP(1) : SNPs within 2kb(10 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR005382 CC chemokine receptor 10
InterPro IPR000355 Chemokine receptor family
InterPro IPR017452 GPCR, rhodopsin-like, 7TM
InterPro IPR000276 G protein-coupled receptor, rhodopsin-like
Protein Ontology PR:000001198 C-C chemokine receptor type 10
References
(Earliest) J:40322 Nibbs RJB, et al., Cloning and characterization of a novel murine beta chemokine receptor, D6. Comparison to three other related macrophage inflammatory protein-1alpha receptors, CCR-1, CCR-3, and CCR-5. J Biol Chem. 1997 May 9;272(19):12495-504
(Latest) J:195497 Agnello D, et al., Intrarectal immunization and IgA antibody-secreting cell homing to the small intestine. J Immunol. 2013 May 1;190(9):4836-47
All references(41)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory