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Ccr10 Gene Detail
Summary
  • Symbol
    Ccr10
  • Name
    chemokine (C-C motif) receptor 10
  • Synonyms
    CCR10, Cmkbr9, GPR2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1096320
    NCBI Gene: 12777
  • Gene Overview
    MyGene.info: CCR10
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:101172998-101175443 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 64.34 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    10 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1096320
protein coding gene Chr11:101172997-101175443 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019186
protein coding gene Chr11:104002748-104005175 (-)
A/J MGP_AJ_G0019154
protein coding gene Chr11:99634918-99637351 (-)
AKR/J MGP_AKRJ_G0019123
protein coding gene Chr11:102732621-102735067 (-)
BALB/cJ MGP_BALBcJ_G0019128
protein coding gene Chr11:100126187-100128633 (-)
C3H/HeJ MGP_C3HHeJ_G0018937
protein coding gene Chr11:102901912-102904367 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019577
protein coding gene Chr11:107221751-107224197 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017203
protein coding gene Chr11:97054037-97056447 (-)
CAST/EiJ MGP_CASTEiJ_G0018491
protein coding gene Chr11:103892983-103895456 (-)
CBA/J MGP_CBAJ_G0018906
protein coding gene Chr11:111681789-111684235 (-)
DBA/2J MGP_DBA2J_G0019018
protein coding gene Chr11:99165753-99168184 (-)
FVB/NJ MGP_FVBNJ_G0019008
protein coding gene Chr11:98712411-98714848 (-)
LP/J MGP_LPJ_G0019087
protein coding gene Chr11:104549220-104551669 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019039
protein coding gene Chr11:111247881-111250318 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019615
protein coding gene Chr11:103051576-103054027 (-)
PWK/PhJ MGP_PWKPhJ_G0018254
protein coding gene Chr11:100217766-100220287 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018046
protein coding gene Chr11:102796307-102798746 (-)
WSB/EiJ MGP_WSBEiJ_G0018540
protein coding gene Chr11:103052508-103054965 (-)



Homology
more
  • Human Ortholog
    CCR10, C-C motif chemokine receptor 10
  • Vertebrate Orthologs
    8
  • Human Ortholog
    CCR10, C-C motif chemokine receptor 10
    Orthology source: HomoloGene, HGNC
  • Synonyms
    GPR2
  • Links
    NCBI Gene ID: 2826
    neXtProt AC: NX_P46092
    UniProt: P46092

  • Chr Location
    17q21.2; chr17:42679402-42681827 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    27 phenotypes from 3 alleles in 4 genetic backgrounds
    24 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for null mutation are viable and fertile, without any detectable neurological abnormalities.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 12777 NCBI Gene Model | MGI Sequence Detail 2446 C57BL/6J ±  kb
transcript NM_007721 RefSeq | MGI Sequence Detail 1725 Not Specified  
polypeptide Q9JL21 UniProt | EBI | MGI Sequence Detail 362 Not Applicable  
For the selected sequence
Protein
Information
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Molecular
Reagents
less
  • All nucleic 7
    cDNA 6
    Other 1

    Microarray probesets 2
References
more
  • Summaries
    All 49
    Developmental Gene Expression 1
    Gene Ontology 7
    Phenotypes 24
  • Earliest
    J:40322 Nibbs RJB, et al., Cloning and characterization of a novel murine beta chemokine receptor, D6. Comparison to three other related macrophage inflammatory protein-1alpha receptors, CCR-1, CCR-3, and CCR-5. J Biol Chem. 1997 May 9;272(19):12495-504
  • Latest
    J:254764 Zaid A, et al., Chemokine Receptor-Dependent Control of Skin Tissue-Resident Memory T Cell Formation. J Immunol. 2017 Oct 1;199(7):2451-2459

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory