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Cyp2g1 Gene Detail
Summary
  • Symbol
    Cyp2g1
  • Name
    cytochrome P450, family 2, subfamily g, polypeptide 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:109612
    NCBI Gene: 13108
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:26808927-26821197 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 15.50 cM, cytoband A3
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    146 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_109612
protein coding gene Chr7:26808892-26821205 (.)
129S1/SvImJ MGP_129S1SvImJ_G0031891
protein coding gene Chr7:25390826-25403604 (+)
A/J MGP_AJ_G0031870
protein coding gene Chr7:24777560-24791315 (+)
AKR/J MGP_AKRJ_G0031800
protein coding gene Chr7:25398445-25413378 (+)
BALB/cJ MGP_BALBcJ_G0031876
protein coding gene Chr7:24971910-24994733 (+)
C3H/HeJ MGP_C3HHeJ_G0031598
protein coding gene Chr7:25816116-25834556 (+)
C57BL/6NJ MGP_C57BL6NJ_G0032338
protein coding gene Chr7:26243951-26265799 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029393
protein coding gene Chr7:26069565-26081396 (+)
CAST/EiJ MGP_CASTEiJ_G0030934
protein coding gene Chr7:19097529-19112006 (+)
CBA/J MGP_CBAJ_G0031563
protein coding gene Chr7:27271974-27288698 (+)
DBA/2J MGP_DBA2J_G0031715
protein coding gene Chr7:24602635-24615599 (+)
FVB/NJ MGP_FVBNJ_G0031670
protein coding gene Chr7:24694175-24706501 (+)
LP/J MGP_LPJ_G0031794
protein coding gene Chr7:25664795-25678357 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0031704
protein coding gene Chr7:26930114-26941484 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0032372
protein coding gene Chr7:24982523-25004401 (+)
PWK/PhJ MGP_PWKPhJ_G0030658
protein coding gene Chr7:19553659-19567496 (+)
SPRET/EiJ MGP_SPRETEiJ_G0030489
protein coding gene Chr7:16111422-16123810 (+)
WSB/EiJ MGP_WSBEiJ_G0031039
protein coding gene Chr7:25258847-25297397 (+)



Homology
more
  • Human Ortholog
    CYP2G1P, cytochrome P450 family 2 subfamily G member 1, pseudogene
  • Vertebrate Orthologs
    15
  • Human Ortholog
    CYP2G1P, cytochrome P450 family 2 subfamily G member 1, pseudogene
    Orthology source: HGNC
  • Synonyms
    CYP2G1, CYP2G2P, CYP2GP1
  • Links
    NCBI Gene ID: 22952
    UniProt: Q6ZSU1

  • Chr Location
    19q13.2; chr19:40890826-40900508 (+)  GRCh38.p7

Human Diseases
less
  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    7 phenotypes from multigenic genotypes
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for disruptions in this gene display an essentially normal phenotype.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 13108 NCBI Gene Model | MGI Sequence Detail 12271 C57BL/6J ±  kb
transcript NM_013809 RefSeq | MGI Sequence Detail 1853 Not Specified  
polypeptide NP_038837 RefSeq | MGI Sequence Detail 494 Not Specified  
For the selected sequence
Protein
Information
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  • UniProt
    1 Sequence
  • InterPro Domains
    IPR001128 Cytochrome P450
    IPR017972 Cytochrome P450, conserved site
    IPR002401 Cytochrome P450, E-class, group I
    IPR008067 Cytochrome P450, E-class, group I, CYP2A-like
    IPR036396 Cytochrome P450 superfamily
Molecular
Reagents
less
  • All nucleic 15
    cDNA 14
    Primer pair 1

    Microarray probesets 2
Other
Accession IDs
less
MGD-MRK-39611
References
more
  • Summaries
    All 30
    Developmental Gene Expression 3
    Diseases 1
    Gene Ontology 3
    Phenotypes 8
  • Earliest
    J:39655 Hua Z, et al., cDNA cloning, heterologous expression, and characterization of mouse CYP2G1, an olfactory-specific steroid hydroxylase. Arch Biochem Biophys. 1997 Apr 15;340(2):208-14
  • Latest
    J:216691 Li L, et al., Identification of cytochrome P450 enzymes critical for lung tumorigenesis by the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK): insights from a novel Cyp2abfgs-null mouse. Carcinogenesis. 2014 Nov;35(11):2584-91

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
01/08/2019
MGI 6.13
The Jackson Laboratory