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Fnbp1 Gene Detail
Summary
  • Symbol
    Fnbp1
  • Name
    formin binding protein 1
  • Synonyms
    1110057E06Rik, 2210010H06Rik, FBP1, FBP17
  • Feature Type
    protein coding gene
  • IDs
    MGI:109606
    NCBI Gene: 14269
  • Gene Overview
    MyGene.info: FNBP1
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:31026206-31142008 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 21.78 cM, cytoband B
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    274 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_109606
 protein coding gene Chr2:31026206-31142028 (-)
129S1/SvImJ MGP_129S1SvImJ_G0025581
 protein coding gene Chr2:29326727-29452196 (-)
A/J MGP_AJ_G0025559
 protein coding gene Chr2:28135583-28253905 (-)
AKR/J MGP_AKRJ_G0025528
 protein coding gene Chr2:29092541-29215984 (-)
BALB/cJ MGP_BALBcJ_G0025555
 protein coding gene Chr2:28270469-28388241 (-)
C3H/HeJ MGP_C3HHeJ_G0025316
 protein coding gene Chr2:29025414-29147981 (-)
C57BL/6NJ MGP_C57BL6NJ_G0026000
 protein coding gene Chr2:30274572-30404499 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023408
 protein coding gene Chr2:26899806-27018500 (-)
CAST/EiJ MGP_CASTEiJ_G0024778
 protein coding gene Chr2:28959883-29081410 (-)
CBA/J MGP_CBAJ_G0025293
 protein coding gene Chr2:31348730-31493071 (-)
DBA/2J MGP_DBA2J_G0025426
 protein coding gene Chr2:27911324-28029632 (-)
FVB/NJ MGP_FVBNJ_G0025389
 protein coding gene Chr2:27753650-27872674 (-)
LP/J MGP_LPJ_G0025512
 protein coding gene Chr2:29235043-29361666 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0025419
 protein coding gene Chr2:31134797-31262876 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0026058
 protein coding gene Chr2:29008722-29133950 (-)
PWK/PhJ MGP_PWKPhJ_G0024525
 protein coding gene Chr2:27786474-27915411 (-)
SPRET/EiJ MGP_SPRETEiJ_G0024325
 protein coding gene Chr2:29151820-29276375 (-)
WSB/EiJ MGP_WSBEiJ_G0024846
 protein coding gene Chr2:29184496-29310442 (-)



Homology
more
  • Human Ortholog
    FNBP1, formin binding protein 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    FNBP1, formin binding protein 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    FBP17
  • Links
    NCBI Gene ID: 23048
    neXtProt AC: NX_Q96RU3
    UniProt: Q96RU3

  • Chr Location
    9q34.11; chr9:129887187-130053846 (-)  GRCh38.p7
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    13
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    65
  • Tissues
    9
  • cDNA Data
    20
  • Literature Summary
    5
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000075415 Ensembl Gene Model | MGI Sequence Detail 115803 C57BL/6J ±  kb
transcript ENSMUST00000113560 Ensembl | MGI Sequence Detail 4726 Not Applicable  
polypeptide ENSMUSP00000109190 Ensembl | MGI Sequence Detail 616 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 20
    cDNA 20

    Microarray probesets 9
Other
Accession IDs
less
MGD-MRK-39605, MGI:1916093, MGI:1917318
References
more
  • Summaries
    All 36
    Developmental Gene Expression 5
    Gene Ontology 5
    Phenotypes 8
  • Earliest
    J:38792 Chan DC, et al., Formin binding proteins bear WWP/WW domains that bind proline-rich peptides and functionally resemble SH3 domains. EMBO J. 1996 Mar 1;15(5):1045-54
  • Latest
    J:231595 Gurdziel K, et al., Transcriptome of the inner circular smooth muscle of the developing mouse intestine: Evidence for regulation of visceral smooth muscle genes by the hedgehog target gene, cJun. Dev Dyn. 2016 May;245(5):614-26
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/15/2019
MGI 6.14 		The Jackson Laboratory