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Hsd3b6
Gene Detail
Symbol

Name
ID
Member of
Hsd3b6
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 6
MGI:109598
Hsd3b cluster
Synonyms
3beta-HSD VI
Feature Type
protein coding gene
Genetic Map
Chromosome 3
42.88 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr3:98805504-98814443 bp, - strand
From VEGA annotation of GRCm38

  8940 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:133013  Vertebrate Homology Class
1 human; 3 mouse; 1 chimpanzee; 1 rhesus macaque

HCOP human homology predictions: HSD3B1, HSD3B2
Protein SuperFamily: bifunctional 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase
Gene Tree: Hsd3b6

Human
homologs
HSD3B1, hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 3283
neXtProt AC: NX_P14060

Human Synonyms: 3BETAHSD, HSD3B, HSDB3, HSDB3A, I, SDR11E1

Human Chr (Location): 1p13.1; chr1:119507124-119515060 (+)  GRCh38.p2

  1 More Homolog(s):
Mutations,
alleles, and
phenotypes
Incidental mutations (data from APF )
Interactions
Hsd3b6 interacts with 99 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (8 records)
Data Summary: Results (162)    Tissues (116)    Images (19)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 100
Western blot 2
RT-PCR 60
cDNA source data(24)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: GEISHA HSD3B2    NEW 
Molecular
reagents
All nucleic(31) Genomic(1) cDNA(24) Primer pair(6)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000006781 (Evidence)
Ensembl Gene Model ENSMUSG00000027869 (Evidence)
Entrez Gene 15497 (Evidence)
UniGene 14435
DFCI TC1582539
DoTS DT.94403119, DT.94403118
NIA Mouse Gene Index U024419
EC 1.1.1.-, 1.1.1.145, 5.3.3.1
Consensus CDS Project CCDS17669.1
International Mouse Phenotyping Consortium Status Hsd3b6
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000006781 VEGA Gene Model | MGI Sequence Detail 8940 C57BL/6J ±  kb
transcript OTTMUST00000015592 VEGA | MGI Sequence Detail 1802 Not Applicable 
polypeptide OTTMUSP00000007181 VEGA | MGI Sequence Detail 373 Not Applicable 

For the selected sequences
All sequences(26) RefSeq(3) UniProt(4)
Polymorphisms
SNPs within 2kb(92 from dbSNP Build 137)    SNPs within 2kb including multiple locations(100)
Protein-related
information
ResourceIDDescription
InterPro IPR002225 3-beta hydroxysteroid dehydrogenase/isomerase
InterPro IPR016040 NAD(P)-binding domain
Protein Ontology PR:000008870 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 6
References
(Earliest) J:39896 Abbaszade IG, et al., Isolation of a new mouse 3beta-hydroxysteroid dehydrogenase isoform, 3beta-HSD VI, expressed during early pregnancy. Endocrinology. 1997 Apr;138(4):1392-9
(Latest) J:211413 Yamamura K, et al., Immunolocalization of murine type VI 3beta-hydroxysteroid dehydrogenase in the adrenal gland, testis, skin, and placenta. Mol Cell Endocrinol. 2014 Jan 25;382(1):131-8
All references(34)
Other
accession IDs
MGD-MRK-39597, MGI:2140104

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory