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Polr2j Gene Detail
Summary
  • Symbol
    Polr2j
  • Name
    polymerase (RNA) II (DNA directed) polypeptide J
  • Synonyms
    14.5kDa, RNA polymerase II subunit RPB14, Rpb11a, Rpo2-4
  • Feature Type
    protein coding gene
  • IDs
    MGI:109582
    NCBI Gene: 20022
  • Gene Overview
    MyGene.info: POLR2J
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:136116691-136122947 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 75.80 cM, cytoband G1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    19 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_109582
protein coding gene Chr5:136116631-136122947 (.)
129S1/SvImJ MGP_129S1SvImJ_G0030200
protein coding gene Chr5:140741801-140748112 (+)
A/J MGP_AJ_G0030168
protein coding gene Chr5:134682591-134688948 (+)
AKR/J MGP_AKRJ_G0030101
protein coding gene Chr5:139035491-139041807 (+)
BALB/cJ MGP_BALBcJ_G0030178
protein coding gene Chr5:136040360-136046732 (+)
C3H/HeJ MGP_C3HHeJ_G0029894
protein coding gene Chr5:139656382-139662691 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030631
protein coding gene Chr5:145977216-145983530 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027851
protein coding gene Chr5:128968250-128974913 (+)
CAST/EiJ MGP_CASTEiJ_G0029304
protein coding gene Chr5:139055744-139062060 (+)
CBA/J MGP_CBAJ_G0029864
protein coding gene Chr5:151681980-151688321 (+)
DBA/2J MGP_DBA2J_G0030015
protein coding gene Chr5:134583199-134589577 (+)
FVB/NJ MGP_FVBNJ_G0029970
protein coding gene Chr5:133736890-133743100 (+)
LP/J MGP_LPJ_G0030104
protein coding gene Chr5:141168335-141174751 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0030002
protein coding gene Chr5:154651074-154659476 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030671
protein coding gene Chr5:138849012-138859316 (+)
PWK/PhJ MGP_PWKPhJ_G0029017
protein coding gene Chr5:133641923-133648456 (+)
SPRET/EiJ MGP_SPRETEiJ_G0028853
protein coding gene Chr5:136401624-136407940 (+)
WSB/EiJ MGP_WSBEiJ_G0029377
protein coding gene Chr5:139575650-139581906 (+)



Homology
more
  • Human Ortholog
    POLR2J, RNA polymerase II subunit J
  • Vertebrate Orthologs
    8
  • Human Ortholog
    POLR2J, RNA polymerase II subunit J
    Orthology source: HomoloGene, HGNC
  • Synonyms
    hRPB14, POLR2J1, RPB11, RPB11A, RPB11m
  • Links
    NCBI Gene ID: 5439
    neXtProt AC: NX_P52435
    UniProt: P52435

  • Chr Location
    7q22.1; chr7:102473100-102478999 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 20022 NCBI Gene Model | MGI Sequence Detail 6257 C57BL/6J ±  kb
transcript NM_011293 RefSeq | MGI Sequence Detail 586 C57BL/6  
polypeptide O08740 UniProt | EBI | MGI Sequence Detail 117 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000033434 DNA-directed RNA polymerase II subunit RPB11
  • InterPro Domains
    IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain
    IPR008193 DNA-directed RNA polymerase Rpb11, 13-16kDa subunit, conserved site
    IPR037685 RNA polymerase RBP11
    IPR036603 RNA polymerase, RBP11-like subunit
Molecular
Reagents
less
  • All nucleic 78
    Genomic 2
    cDNA 76

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-39581
References
more
  • Summaries
    All 40
    Developmental Gene Expression 4
    Gene Ontology 7
    Phenotypes 9
  • Earliest
    J:38275 Korobko IV, et al., Protein interaction cloning in yeast of the mouse third largest RNA polymerase II subunit, mRPB31. Gene. 1997 Jan 31;185(1):1-4
  • Latest
    J:244911 Zhang M, et al., Post-transcriptional regulation of mouse neurogenesis by Pumilio proteins. Genes Dev. 2017 Aug 9;

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory