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Taf1a Gene Detail
Summary
  • Symbol
    Taf1a
  • Name
    TATA-box binding protein associated factor, RNA polymerase I, A
  • Synonyms
    mTAFI48
  • Feature Type
    protein coding gene
  • IDs
    MGI:109578
    NCBI Gene: 21339
  • Gene Overview
    MyGene.info: TAF1A
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:183388981-183410198 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, Syntenic
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    77 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_109578
protein coding gene Chr1:183388885-183410201 (.)
129S1/SvImJ MGP_129S1SvImJ_G0016904
protein coding gene Chr1:190049799-190072786 (+)
A/J MGP_AJ_G0016883
protein coding gene Chr1:182279657-182300997 (+)
AKR/J MGP_AKRJ_G0016848
protein coding gene Chr1:187702202-187723350 (+)
BALB/cJ MGP_BALBcJ_G0016841
protein coding gene Chr1:182920539-182940923 (+)
C3H/HeJ MGP_C3HHeJ_G0016665
protein coding gene Chr1:188497324-188521133 (+)
C57BL/6NJ MGP_C57BL6NJ_G0017304
protein coding gene Chr1:196138140-196161297 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015011
protein coding gene Chr1:173334223-173354724 (+)
CAST/EiJ MGP_CASTEiJ_G0016248
protein coding gene Chr1:187889462-187911301 (+)
CBA/J MGP_CBAJ_G0016639
protein coding gene Chr1:203453084-203481280 (+)
DBA/2J MGP_DBA2J_G0016745
protein coding gene Chr1:181061284-181081285 (+)
FVB/NJ MGP_FVBNJ_G0016741
protein coding gene Chr1:179193631-179213547 (+)
LP/J MGP_LPJ_G0016820
protein coding gene Chr1:191228412-191254117 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016773
protein coding gene Chr1:210387485-210410714 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0017341
protein coding gene Chr1:187527121-187549585 (+)
PWK/PhJ MGP_PWKPhJ_G0016035
protein coding gene Chr1:180265071-180285538 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015811
protein coding gene Chr1:186488324-186510376 (+)
WSB/EiJ MGP_WSBEiJ_G0016310
protein coding gene Chr1:187701264-187721733 (+)



Homology
more
  • Human Ortholog
    TAF1A, TATA-box binding protein associated factor, RNA polymerase I subunit A
  • Vertebrate Orthologs
    10
  • Human Ortholog
    TAF1A, TATA-box binding protein associated factor, RNA polymerase I subunit A
    Orthology source: HomoloGene, HGNC
  • Synonyms
    MGC:17061, RAFI48, SL1, TAFI48
  • Links
    NCBI Gene ID: 9015
    neXtProt AC: NX_Q15573
    UniProt: Q15573

  • Chr Location
    1q41; chr1:222557902-222590096 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
  • All Sequences
  • RefSeq
  • UniProt
  • UniGene
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000072258 Ensembl Gene Model | MGI Sequence Detail 21218 C57BL/6J ±  kb
transcript ENSMUST00000097043 Ensembl | MGI Sequence Detail 1472 Not Applicable  
polypeptide ENSMUSP00000094808 Ensembl | MGI Sequence Detail 453 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    6 Sequences
  • Protein Ontology
    PR:000016020 TATA box-binding protein-associated factor RNA polymerase I subunit A
  • InterPro Domains
    IPR016629 RNA polymerase I, subunit A (TATA-binding protein-associated factor)
    IPR039495 TATA box-binding protein-associated factor RNA polymerase I subunit A-like
Molecular
Reagents
less
  • All nucleic 45
    cDNA 45

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-39577
References
more
  • Summaries
    All 28
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 5
  • Earliest
    J:39012 Heix J, et al., Cloning of murine RNA polymerase I-specific TAF factors: conserved interactions between the subunits of the species-specific transcription initiation factor TIF-IB/SL1. Proc Natl Acad Sci U S A. 1997 Mar 4;94(5):1733-8
  • Latest
    J:216243 Murano K, et al., Reconstitution of human rRNA gene transcription in mouse cells by a complete SL1 complex. J Cell Sci. 2014 Aug 1;127(Pt 15):3309-19

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory