About   Help   FAQ
Tectb
Gene Detail
 Symbol
Name
ID
Tectb
tectorin beta
MGI:109574
Synonyms [b]-tectorin, Tctnb
Feature Type protein coding gene
Genetic Map
Chromosome 19
51.13 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr19:55180733-55196313 bp, + strand
From VEGA annotation of GRCm38

  15581 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:7568  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Tectb

Human
homologs
Human Homolog TECTB, tectorin beta
NCBI Gene ID 6975
neXtProt AC  NX_Q96PL2
Human Chr (Location)  10q25-q26; chr10:112283455-112305035 (+)  GRCh38
Alleles
and
phenotypes
All alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygotes for a null allele show an enlarged tectorial membrane with a disrupted striated-sheet matrix, absence of the marginal band, and low-frequency hearing loss. However, basilar-membrane and neural tuning are both enhanced in high-frequency cochlear regions, with little loss in sensitivity.
 
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process sensory perception of sound
Component anchored component of membrane, extracellular region, ...
Function extracellular matrix structural constituent
External Resources: FuncBase
Expression
Literature Summary: (7 records)
Data Summary: Results (41)    Tissues (20)    Images (16)
Theiler Stages: 19, 20, 21, 22, 28
Assay TypeResults
Immunohistochemistry 4
RNA in situ 37
cDNA source data(15)
External Resources: GEO   ArrayExpress
Molecular
reagents
All nucleic(18) Genomic(1) cDNA(16) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000028257 (Evidence)
Ensembl Gene ModelENSMUSG00000024979 (Evidence)
Entrez Gene21684 (Evidence)
UniGene42139
DFCITC1580059, TC1599864
DoTSDT.55164821, DT.99848228
NIA Mouse Gene IndexU019586
Consensus CDS ProjectCCDS29907.1
International Mouse Knockout Project StatusTectb
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000028257 VEGA Gene Model | MGI Sequence Detail 15581 C57BL/6J ±  kb
transcript OTTMUST00000070022 VEGA | MGI Sequence Detail 1349 Not Applicable 
polypeptide OTTMUSP00000035638 VEGA | MGI Sequence Detail 339 Not Applicable 

For the selected sequences
All sequences(43) RefSeq(6) UniProt(5)
Polymorphisms SNPs within 2kb(223 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001507 Zona pellucida domain
InterPro IPR017977 Zona pellucida domain, conserved site
Protein Ontology PR:000016223 beta-tectorin
References (Earliest) J:39295 Legan PK, et al., The mouse tectorins. Modular matrix proteins of the inner ear homologous to components of the sperm-egg adhesion system. J Biol Chem. 1997 Mar 28;272(13):8791-801
(Latest) J:189624 Son EJ, et al., Developmental gene expression profiling along the tonotopic axis of the mouse cochlea. PLoS One. 2012;7(7):e40735
All references(39)
Other
accession IDs
MGD-MRK-39573

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/15/2014
MGI 5.18
The Jackson Laboratory